Evidence map›Paper›PMID 28927201›Full record

ReviewJournal of the Pediatric Infectious Diseases Society2017

Recognition and Clinical Presentation of Invasive Fungal Disease in Neonates and Children.

Jill King, Zoi-Dorothea Pana, Thomas Lehrnbecher, William J Steinbach, Adilia Warris

Abstract readReview
In one paragraph

Review in Journal of the Pediatric Infectious Diseases Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Brazilian task force for the management of mucormycosis.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Guideline
  4. Article
  5. Neonatal Invasive Candidiasis: Current Concepts.Indian journal of pediatrics · 2025
    Review
  6. Mucormycosis.Infectious disease clinics of North America · 2025
    Review
  7. Article
  8. Review
  9. Diagnostic and Therapeutic Challenge Caused byPathogens (Basel, Switzerland) · 2024
    Review
  10. Review
  11. Article
  12. Osteoarticular Mycoses.Clinical microbiology reviews · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Gastrointestinal mucormycosis in the pediatric age group: an evolving disease.International journal of clinical and experimental pathology · 2022
    Article
  17. Antibiotic-induced depletion ofFrontiers in cellular and infection microbiology · 2022
    Article
  18. Cryptococcus liquefaciens isolated from the hand of a healthcare professional in a neonatal intensive care unit.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jill KingAberdeen Fungal Group, Medical Research Council Centre for Medical Mycology, Institute of Medical Sciences, University of Aberdeen, and the Royal Aberdeen Children's Hospital, United Kingdom.
Zoi-Dorothea PanaHospital Epidemiology and Infection Control, Division of Infectious Diseases, Johns Hopkins Hospital, Baltimore, Maryland.
Thomas LehrnbecherDivision of Paediatric Haematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.
William J SteinbachDivision of Pediatric Infectious Diseases, Department of Pediatrics, and Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina.
Adilia WarrisAberdeen Fungal Group, Medical Research Council Centre for Medical Mycology, Institute of Medical Sciences, University of Aberdeen, and the Royal Aberdeen Children's Hospital, United Kingdom.

Funding

Medical Research Council MR/N006364/1Wellcome Trust 097377
6 · The paper itself

Abstract

Invasive fungal diseases (IFDs) are devastating opportunistic infections that result in significant morbidity and death in a broad range of pediatric patients, particularly those with a compromised immune system. Recognizing them can be difficult, because nonspecific clinical signs and symptoms or isolated fever are frequently the only presenting features. Therefore, a high index of clinical suspicion is necessary in patients at increased risk of IFD, which requires knowledge of the pediatric patient population at risk, additional predisposing factors within this population, and the clinical signs and symptoms of IFD. With this review, we aim to summarize current knowledge regarding the recognition and clinical presentation of IFD in neonates and children.

Indexed as

AspergillosisCandidiasisChildCritical IllnessCross InfectionHematologic NeoplasmsHospitalizationHumansImmunocompromised HostImmunologic Deficiency SyndromesInfant, NewbornInfant, PrematureInfant, Premature, DiseasesIntensive Care Units, PediatricInvasive Fungal InfectionsMucormycosisclinical presentationinvasive aspergillosisinvasive candidiasisinvasive fungal diseasepediatric patients

Identifiers

PMID28927201
PMCPMC5907856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.