Evidence map›Paper›PMID 28927114›Full record

ArticleOncology letters2017

MicroRNA-383-5p acts as a prognostic marker and inhibitor of cell proliferation in lung adenocarcinoma by cancerous inhibitor of protein phosphatase 2A.

Shasha Zhao, Xinyuan Gao, Shuzhi Zang, Yunxia Li, Xianjun Feng, Xiaomei Yuan

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
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  10. Target c-Myc to treat pancreatic cancer.Cancer biology & therapy · 2022
    Article
  11. Review
  12. Article
  13. Review
  14. MicroRNA-383: A tumor suppressor miRNA in human cancer.Frontiers in cell and developmental biology · 2022
    Review
  15. DNA methylation ofAging · 2021
    Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shasha ZhaoDepartment of Respiratory Medicine, The First Hospital Affiliated to The Xinxiang Medical College, Xinxiang, Henan 453100, P.R. China.
Xinyuan GaoDepartment of Respiratory Medicine, The First Hospital Affiliated to The Xinxiang Medical College, Xinxiang, Henan 453100, P.R. China.
Shuzhi ZangDepartment of Respiratory Medicine, The First Hospital Affiliated to The Xinxiang Medical College, Xinxiang, Henan 453100, P.R. China.
Yunxia LiDepartment of Respiratory Medicine, The First Hospital Affiliated to The Xinxiang Medical College, Xinxiang, Henan 453100, P.R. China.
Xianjun FengDepartment of Respiratory Medicine, The First Hospital Affiliated to The Xinxiang Medical College, Xinxiang, Henan 453100, P.R. China.
Xiaomei YuanDepartment of Respiratory Medicine, The First Hospital Affiliated to The Xinxiang Medical College, Xinxiang, Henan 453100, P.R. China.
Xinxiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the leading cause of cancer-associated mortality worldwide. MicroRNAs (miRNAs/miRs) serve a role in the occurrence and development of lung cancer. The aim of the present study was to analyze the expression and function of the proliferation-associated miR-383-5p in lung adenocarcinoma (LAC). Samples of human LAC and matched adjacent normal lung tissues were surgically removed, and miR-383-5p expression and the pathological characteristics of lung adenocarcinoma were investigated. The present study revealed that miR-383-5p expression level was significantly decreased in LAC tissues and its expression levels were markedly associated with tumor size and differentiation. Overexpression of miR-383-5p in A549 and H1299 LAC cell lines inhibited cell proliferation by G

Indexed as

cancerous inhibitor of protein phosphatase 2Alung adenocarcinomamicroRNA-383-5pproliferation

Identifiers

PMID28927114
PMCPMC5588061
OpenAlexW2739164858

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.