Evidence map›Paper›PMID 28926791›Full record

ArticleDrug and alcohol dependence2017

Prevalence and correlates of sleep-related problems in adults receiving medical cannabis for chronic pain.

James A Cranford, J Todd Arnedt, Deirdre A Conroy, Kipling M Bohnert, Carrie Bourque, Frederic C Blow, Mark Ilgen

Registry-linked trialAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03964974 (Reducing Cannabis Use for Sleep Among Adults Using Medical Cannabis), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03964974 nacompletednot on this mapstarted 2020, after this paper: background citation

Reducing Cannabis Use for Sleep Among Adults Using Medical Cannabis

TypeinterventionalSponsorUniversity of MichiganRan2020 to 2021Enrolled57ConditionsInsomnia Chronic, Cannabis UseArmsCognitive Behavioral Therapy for Insomnia in Cannabis Users (CBTi-CB), Sleep Hygiene Education (SHE)
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Interactions between cannabis use and chronic pain on sleep architecture: Findings from in-home EEG recordings.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Cannabis and sleep disorders: not ready for prime time? A qualitative scoping review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Effect of prenatal marijuana exposure on sleep wake cycles and amplitude-integrated electroencephalogram (aEEG).Journal of perinatology : official journal of the California Perinatal Association · 2021
    Article
  17. Article
  18. Daily associations between sleep and opioid use among adults with comorbid symptoms of insomnia and fibromyalgia.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

James A CranfordDepartment of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI, 48109-2700, United States. Electronic address: jcranfor@med.umich.edu.
J Todd ArnedtDepartment of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI, 48109-2700, United States.
Deirdre A ConroyDepartment of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI, 48109-2700, United States.
Kipling M BohnertDepartment of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI, 48109-2700, United States; VA Center for Clinical Management Research (CCMR), Veterans Health Administration, 2215 Fuller Road, Mail Stop 152, Ann Arbor, MI, 48105, United States.
Carrie BourqueDepartment of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI, 48109-2700, United States.
Frederic C BlowDepartment of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI, 48109-2700, United States; VA Center for Clinical Management Research (CCMR), Veterans Health Administration, 2215 Fuller Road, Mail Stop 152, Ann Arbor, MI, 48105, United States.
Mark IlgenDepartment of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI, 48109-2700, United States; VA Center for Clinical Management Research (CCMR), Veterans Health Administration, 2215 Fuller Road, Mail Stop 152, Ann Arbor, MI, 48105, United States.
University of Michigan–Ann Arbor · USVeterans Health Administration · USVA Center for Clinical Management Research · US

Funding

Medical marijuana: Longitudinal trajectories in use, pain and functioningR01DA033397 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ILGEN, MARK A. · 2013 to 2016
$2.2M
NIDA NIH HHS R01 DA033397
6 · The paper itself

Abstract

purposeTo examine the prevalence and correlates of sleep problems in a sample of medical cannabis patients. PROCEDURES: Adults ages 21 and older (N=801,M age=45.8) who were seeking medical cannabis certification (either for the first time or as a renewal) for chronic pain at medical cannabis clinics in southern Michigan completed baseline measures of cannabis use, sleep, pain, and other related constructs.

findingsOver half of the sample (59%) met criteria for past 1-month sleep disturbance, defined as at least one sleep problem occurring on 15 or more nights in the past month. Most participants (86%) reported that sleep problems were due to their current pain. Approximately 80% of participants reported using cannabis in the past 6 months to improve sleep and, among these participants, cannabis was rated as helpful for improving sleep. Sleep-related cannabis side effects were rare (35%), but sleep-related cannabis withdrawal symptoms were relatively common (65%). Statistically significant correlates of past 1-month sleep disturbance included a) being female, b) being white, c) being on disability, d) not having a medical cannabis card, and e) frequency of using cannabis to help sleep.

conclusionsSleep problems are highly prevalent and frequent in medical cannabis patients and are closely tied to pain. Sleep-related cannabis withdrawal symptoms are relatively common but their clinical relevance is unknown. The association between frequency of cannabis use to help sleep with higher odds of sleep problems will need to be clarified by longitudinal studies.

Indexed as

CannabisAdultChronic PainHumansMedical MarijuanaMichiganPrevalenceSleep Wake DisordersSubstance-Related DisordersSubstance Withdrawal SyndromeMedical MarijuanaCorrelates of sleep disturbanceMedical cannabisPainSleepSleep disturbance

Identifiers

PMID28926791
PMCPMC5648597
OpenAlexW2753305297

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.