Trial reportBritish journal of cancer2017
The Improving Rural Cancer Outcomes Trial: a cluster-randomised controlled trial of a complex intervention to reduce time to diagnosis in rural cancer patients in Western Australia.
Trial report in British journal of cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- A systematic review of interventions to recognise, refer and diagnose patients with lung cancer symptoms.NPJ primary care respiratory medicine · 2022Pooled it
- Development, validation and effectiveness of diagnostic prediction tools for colorectal cancer in primary care: a systematic review.BMC cancer · 2020Pooled it
- Cancer diagnostic tools to aid decision-making in primary care: mixed-methods systematic reviews and cost-effectiveness analysis.Health technology assessment (Winchester, England) · 2020Pooled it
- Contemporary Educational Interventions for General Practitioners (GPs) in Primary Care Settings in Australia: A Systematic Literature Review.Frontiers in public health · 2019Pooled it
- Randomised controlled trial and economic evaluation of a targeted cancer awareness intervention for adults living in deprived areas of the UK.British journal of cancer · 2021Trial
- Trial
- Educational Interventions to Reduce Cancer Diagnostic Delays in Primary Care: A Scoping Review.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026Review
- Interventions to Improve Timely Detection and Diagnosis of Cancer Among the Adult Population: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Implementation strategies for evidence-based healthcare interventions in rural and remote settings: a scoping review.The Lancet regional health. Western Pacific · 2026Review
- Adaptive designs for trials aiming to optimise implementation strategies and the effect of an additional interim analysis: a simulation study.BMC medical research methodology · 2025Article
- Rural Cancer Survivors' Perceived Delays in Seeking Medical Attention, Diagnosis and Treatment: Findings From a Large Qualitative Study.Cancer medicine · 2025Article
- 'ThinkCancer!': randomised feasibility trial of a novel practice-based early cancer diagnosis intervention.BJGP open · 2024Article
- Hidden systems in primary care cancer detection: an embedded qualitative intervention development study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2024Article
- Article
- Population-based study on coverage and healthcare processes for cancer during implementation of national healthcare insurance in Indonesia.The Lancet regional health. Southeast Asia · 2022Article
- Disparities in outcomes among patients diagnosed with cancer in proximity to an emergency department visit.Scientific reports · 2022Observational
- Using cancer risk algorithms to improve risk estimates and referral decisions.Communications medicine · 2022Article
- Interventions to improve early cancer diagnosis of symptomatic individuals: a scoping review.BMJ open · 2021Article
- Barriers and facilitators to implementing a cancer risk assessment tool (QCancer) in primary care: a qualitative study.Primary health care research & development · 2021Article
- Approaches to diagnosing cancer earlier in general practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
13 authors at 8 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRural Australians have poorer survival for most common cancers, due partially to later diagnosis. Internationally, several initiatives to improve cancer outcomes have focused on earlier presentation to healthcare and timely diagnosis. We aimed to measure the effect of community-based symptom awareness and general practice-based educational interventions on the time to diagnosis in rural patients presenting with breast, prostate, colorectal or lung cancer in Western Australia.
methods2 × 2 factorial cluster randomised controlled trial. Community Intervention: cancer symptom awareness campaign tailored for rural Australians. GP intervention: resource card with symptom risk assessment charts and local cancer referral pathways implemented through multiple academic detailing visits. Trial Area A received the community symptom awareness and Trial Area B acted as the community campaign control region. Within both Trial Areas general practices were randomised to the GP intervention or control. PRIMARY OUTCOME: total diagnostic interval (TDI).
results1358 people with incident breast, prostate, colorectal or lung cancer were recruited. There were no significant differences in the median or ln mean TDI at either intervention level (community intervention vs control: median TDI 107.5 vs 92 days; ln mean difference 0.08 95% CI -0.06-0.23 P=0.27; GP intervention vs control: median TDI 97 vs 96.5 days; ln mean difference 0.004 95% CI -0.18-0.19 P=0.99). There were no significant differences in the TDI when analysed by factorial design, tumour group or sub-intervals of the TDI.
conclusionsThis is the largest trial to test the effect of community campaign or GP interventions on timeliness of cancer diagnosis. We found no effect of either intervention. This may reflect limited dose of the interventions, or the limited duration of follow-up. Alternatively, these interventions do not have a measurable effect on time to cancer diagnosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.