Observational studyAnesthesiology2017
Recovery after Nulliparous Birth: A Detailed Analysis of Pain Analgesia and Recovery of Function.
Observational study in Anesthesiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03472521 (Prevention of Persistent Pain and Opioid Use in Mothers - POMS), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevention of Persistent Pain and Opioid Use in Mothers - POMS
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Evaluation of Domains of Patient-Reported Outcome Measures for Recovery After Childbirth: A Scoping and Systematic Review.JAMA network open · 2020Pooled it
- Trial
- Ultrasound-Guided Transversalis Fascia Plane Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia After Repeat Cesarean Delivery: A Prospective Observational Study.Healthcare (Basel, Switzerland) · 2026Article
- Profiling Postpartum Recovery After Scheduled Cesarean Delivery With Neuraxial Anesthesia: A Longitudinal Cohort Study.Anesthesia and analgesia · 2025Article
- What delivery-related factors affect postpartum recovery? A systematic review.AJOG global reports · 2025Review
- The impact of different strategies for modeling associations between medications at low doses and health outcomes: a simulation study and practical application to postpartum opioid use.American journal of epidemiology · 2025Article
- Predicting the Severity of Acute Pain after Cesarean Delivery: A Narrative Review.Current pain and headache reports · 2024Review
- The development of multidisciplinary convalescence recommendations after childbirth: a modified Delphi study.AJOG global reports · 2024Article
- Care Bundles: Enhanced Recovery After Delivery.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2023Article
- Measuring enhanced recovery in obstetrics: a narrative review.AJOG global reports · 2023Article
- Physical and psychological recovery after vaginal childbirth with and without epidural analgesia: A prospective cohort study.PloS one · 2023Article
- The risk of serious opioid-related events associated with common opioid prescribing regimens in the postpartum period after cesarean delivery.American journal of obstetrics & gynecology MFM · 2021Article
- Influence of Catheter-Incision Congruency in Epidural Analgesia on Postcesarean Pain Management: A Single-Blinded Randomized Controlled Trial.Journal of personalized medicine · 2021Article
- The Current Consideration, Approach, and Management in Postcesarean Delivery Pain Control: A Narrative Review.Anesthesiology research and practice · 2021Review
- Evaluation of a new departmental policy to decrease routine opioid prescribing after vaginal delivery.American journal of obstetrics & gynecology MFM · 2020Article
- Factors associated with persistent pain after childbirth: a narrative review.British journal of anaesthesia · 2020Review
- Opioid prescribing after childbirth: overprescribing and chronic use.Current opinion in obstetrics & gynecology · 2019Review
- Article
- Frequency of Opioid Dispensing After Vaginal Delivery.Obstetrics and gynecology · 2018Article
- Prediction of outliers in pain, analgesia requirement, and recovery of function after childbirth: a prospective observational cohort study.British journal of anaesthesia · 2018Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe majority of parturients in the United States first return for evaluation by their obstetric practitioner 6 weeks after delivery. As such, there is little granular data on the pain experience, analgesic requirements, and functional recovery during the postpartum period. This prospective observational study was performed to evaluate these factors to provide expectations for patients.
methodsA total of 213 nulliparous women were enrolled and assessed daily until they completed 3 outcomes: (1) pain resolution; (2) opioid cessation; and (3) self-assessed functional recovery from delivery. The primary endpoint, pain- and opioid-free functional recovery, was the time required to reach all three of the endpoints. Pain burden was assessed as the area under the curve created by plotting the daily numerical pain rating scale against the days required to attain pain resolution. Times to attain study endpoints after cesarean delivery and vaginal delivery were compared using survival analysis.
resultsAfter vaginal delivery, days required for pain and opioid-free functional recovery (median [interquartile range (IQR)]) were 19 [11 to 26], for opioid cessation 0 [0 to 2], termination of all analgesic (including nonsteroidal antiinflammatories and acetaminophen) 11 [5 to 17], and pain resolution 14 [7 to 24]. Achievement of these endpoints after cesarean delivery required 27 [19 to 40], 9 [5 to 12], 16 [11 to 24], and 21 [14 to 27] days, respectively.
conclusionsThere is clinically significant variability between healthy nulliparous parturients in the pain experience, opioid use, and functional recovery after childbirth following vaginal and cesarean delivery. Recovery to predelivery function is similar after vaginal and cesarean delivery, and approximately half of the variance was explained by pain burden.
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Registered trials
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