ArticleInvestigative radiology2018
Photon-Counting Computed Tomography for Vascular Imaging of the Head and Neck: First In Vivo Human Results.
Article in Investigative radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 1 of them a synthesis that pooled it.
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Who cites it
100 citing papers in PubMed, 1 synthesis or guideline pooled it, 180 citations in OpenAlex.
- Computed Tomography of the Head : A Systematic Review on Acquisition and Reconstruction Techniques to Reduce Radiation Dose.Clinical neuroradiology · 2023Pooled it
- Photon-counting detector CT vs energy-integrating detector CT for the diagnosis of arterial dissection in the cervicocerebral region: A single-center case series.Radiology case reports · 2026Article
- Photon-counting CT in head and neck radiology: bridging detector physics and clinical applications.European radiology · 2026Review
- Spectral CT and Photon-counting Detector CT: Principles and Applications in Neuroradiology.Radiology. Imaging cancer · 2026Review
- Where Does the Signal Go? Technical Challenges of CT Perfusion in Lacunar and Infratentorial Stroke.Tomography (Ann Arbor, Mich.) · 2026Review
- Technical advances and clinical impact of photon-counting computed tomography angiography for peripheral artery disease.Journal of vascular surgery cases and innovative techniques · 2026Article
- Photon-Counting Detector CT-Based Virtual Monoenergetic Imaging With Metal Artifact Reduction for Endodontic Diagnostics.International dental journal · 2026Article
- Differentiating Hemorrhage and Contrast Extravasation After Mechanical Thrombectomy Using Virtual Non-Contrast Photon-Counting CT.Clinical neuroradiology · 2026Article
- Photon-counting CT in neuroradiology: a comprehensive SWOT analysis.European radiology · 2026Review
- Pre-operative visualization of cerebral vasculature using photon-counting CT ultra-high resolution pure lumen imaging.Brain & spine · 2026Article
- Reduction of radiation exposure and preserved image quality using photon-counting detector cardiac computed tomography without electrocardiographic gating in children with congenital heart disease.European radiology · 2026Article
- A cone-beam photon-counting CT dataset for spectral image reconstruction and deep learning.Scientific data · 2025Article
- High-pitch photon-counting detector computed tomography angiography of the coronary arteries: Qualitative and quantitative evaluation of monoenergetic image reconstructions.European journal of radiology open · 2025Article
- Photon-Counting Computed Tomography in Thoracic Surgery: A Narrative Review of Current and Future Applications.Cancers · 2025Review
- Clinical applications of portable CT scanners.The British journal of radiology · 2025Review
- Contrast medium dose optimization in the era of multi-energy CT.Japanese journal of radiology · 2025Review
- Ultra-high resolution CT angiography for the assessment of intracranial stents and flow diverters using photon counting detector CT.Journal of neurointerventional surgery · 2025Article
- Postoperative assessment of fracture reduction and osteosynthesis materials using photon-counting detector CT in maxillofacial trauma - a pilot study.Oral and maxillofacial surgery · 2025Article
- Stenosis quantification in high-pitch photon-counting coronary CT angiography: in vitro and in vivo impact of reconstruction kernel types and sharpness levels.European radiology experimental · 2025Article
- Advancing Preoperative Planning in Perforator Flap Surgery with Photon-Counting Computed Tomography Angiography: Less Challenges with More Precision.Aesthetic plastic surgery · 2025Article
40 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
purposeThe purpose of this study was to evaluate image quality of a spectral photon-counting detector (PCD) computed tomography (CT) system for evaluation of major arteries of the head and neck compared with conventional single-energy CT scans using energy-integrating detectors (EIDs).
methodsIn this institutional review board-approved study, 16 asymptomatic subjects (7 men) provided informed consent and received both PCD and EID contrast-enhanced CT scans of the head and neck (mean age, 58 years; range, 46-75 years). Tube settings were (EID: 120 kVp/160 mA vs PCD: 140 kVp/108 mA) for all volunteers. Quantitative analysis included measurements of mean attenuation, image noise, and contrast-to-noise ratio (CNR). Spectral PCD data were used to reconstruct virtual monoenergetic images and iodine maps. A head phantom was used to validate iodine concentration measurements in PCD images only. Two radiologists blinded to detector type independently scored the image quality of different segments of the arteries, as well as diagnostic acceptability, image noise, and severity of artifacts of the PCD and EID images. Reproducibility was assessed with intraclass correlation coefficient. Linear mixed models that account for within-subject correlation of analyzed arterial segments were used. Linear regression and Bland-Altman analysis with 95% limits of agreement were used to calculate the accuracy of material decomposition.
resultsPhoton-counting detector image quality scores were significantly higher compared with EID image quality scores with lower image noise (P < 0.01) and less image artifacts (P < 0.001). Photon-counting detector image noise was 9.1% lower than EID image noise (8.0 ± 1.3 HU vs 8.8 ± 1.5 HU, respectively, P < 0.001). Arterial segments showed artifacts on EID images due to beam hardening that were not present on PCD images. On PCD images of the head phantom, there was excellent correlation (R = 0.998) between actual and calculated iodine concentrations without significant bias (bias: -0.4 mg/mL [95% limits of agreements: -1.1 to 0.4 mg/mL]). Iodine maps had 20.7% higher CNR compared with nonspectral PCD (65.2 ± 9.0 vs 54.0 ± 4.5, P = 0.01), and virtual monoenergetic image at 70 keV showed similar CNR to nonspectral images (52.6 ± 4.2 vs 54.0 ± 4.5, P = 0.39).
conclusionsPhoton-counting CT has the potential to improve the image quality of carotid and intracranial CT angiography compared with single-energy EID CT.
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