Evidence map›Paper›PMID 28926241›Full record

ArticleJournal of the American Chemical Society2017

Supramolecular Chemistry Targeting Proteins.

Sam van Dun, Christian Ottmann, Lech-Gustav Milroy, Luc Brunsveld

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Protein Recognition and Assembly by a Phosphocavitand.Journal of the American Chemical Society · 2025
    Article
  9. Molecular Tweezers Block the Functional Pore of a Protein Machine.Journal of the American Chemical Society · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Article
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  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sam van DunLaboratory of Chemical Biology and Institute for Complex Molecular Systems, Department of Biomedical Engineering, Eindhoven University of Technology , Den Dolech 2, 5612 AZ Eindhoven, The Netherlands.
Christian OttmannLaboratory of Chemical Biology and Institute for Complex Molecular Systems, Department of Biomedical Engineering, Eindhoven University of Technology , Den Dolech 2, 5612 AZ Eindhoven, The Netherlands.ORCID 0000-0001-7315-0315
Lech-Gustav MilroyLaboratory of Chemical Biology and Institute for Complex Molecular Systems, Department of Biomedical Engineering, Eindhoven University of Technology , Den Dolech 2, 5612 AZ Eindhoven, The Netherlands.
Luc BrunsveldLaboratory of Chemical Biology and Institute for Complex Molecular Systems, Department of Biomedical Engineering, Eindhoven University of Technology , Den Dolech 2, 5612 AZ Eindhoven, The Netherlands.ORCID 0000-0001-5675-511X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The specific recognition of protein surface elements is a fundamental challenge in the life sciences. New developments in this field will form the basis of advanced therapeutic approaches and lead to applications such as sensors, affinity tags, immobilization techniques, and protein-based materials. Synthetic supramolecular molecules and materials are creating new opportunities for protein recognition that are orthogonal to classical small molecule and protein-based approaches. As outlined here, their unique molecular features enable the recognition of amino acids, peptides, and even whole protein surfaces, which can be applied to the modulation and assembly of proteins. We believe that structural insights into these processes are of great value for the further development of this field and have therefore focused this Perspective on contributions that provide such structural data.

Indexed as

Amino AcidsAnimalsBridged-Ring CompoundsDrug Delivery SystemsHumansLigandsMacrocyclic CompoundsModels, MolecularPeptidesProtein BindingProtein ConformationProteinsAmino AcidsBridged-Ring CompoundsLigandsMacrocyclic CompoundsPeptidesProteins

Identifiers

PMID28926241
PMCPMC5639466

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.