Evidence map›Paper›PMID 28926036›Full record

ArticleChemical communications (Cambridge, England)2017

Polymer nanodiscs and macro-nanodiscs of a varying lipid composition.

Venkata Sudheer Kumar Ramadugu, Giacomo Maria Di Mauro, Thirupathi Ravula, Ayyalusamy Ramamoorthy

RetractedAbstract readRetracted Publication
In one paragraph

Article in Chemical communications (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Impact of membrane curvature on amyloid aggregation.Biochimica et biophysica acta. Biomembranes · 2018
    Review
  2. Article
  3. Article
  4. Formation of pH-Resistant Monodispersed Polymer-Lipid Nanodiscs.Angewandte Chemie (International ed. in English) · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Venkata Sudheer Kumar RamaduguBiophysics Program and Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109-1055, USA. ramamoor@umich.edu.
Giacomo Maria Di Mauro
Thirupathi Ravula
Ayyalusamy Ramamoorthy

Funding

Supplement: Investigation of Membrane-Bound Cytochromes-P450-b5 InteractionsR01GM084018 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAMAMOORTHY, AYYALUSAMY · 2009 to 2018
$3.8M
Membrane interaction and disruption by the Alzheimer's amyloid-beta peptideR01AG048934 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAMAMOORTHY, AYYALUSAMY · 2016 to 2020
$2.0M
NIA NIH HHS R01 AG048934NIGMS NIH HHS R01 GM084018
6 · The paper itself

Abstract

Polymer lipid nanodiscs have enabled some exciting structural biology and nanobiotechnology applications. The use of a small molecular weight polymer (SMA-EA) has been demonstrated to dramatically increase the size of nanodiscs (up to ∼60 nm diameter). Here, we report the first demonstration of the formation of macro-nanodiscs for a variety of lipids, and solid-state NMR experiments utilizing their magnetic-alignment properties.

Identifiers

PMID28926036
PMCPMC5621649

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.