Evidence map›Paper›PMID 28925976›Full record

ReviewToxins2017

Shiga Toxin Therapeutics: Beyond Neutralization.

Gregory Hall, Shinichiro Kurosawa, Deborah J Stearns-Kurosawa

Open access · goldAbstract readReview
In one paragraph

Review in Toxins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Prevalence of selected Shiga toxin-producingJournal of medical microbiology · 2026
    Article
  5. Redefining Shiga toxin-induced human cell death as NLRP1- and gasdermin E-mediated pyroptosis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Poultry pathogenicity, antimicrobial resistance, and one health genomic characterization of ST83 Escherichia coli.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  7. Article
  8. Review
  9. The diverse landscape of AB5-type toxins.Engineering microbiology · 2023
    Review
  10. Article
  11. Article
  12. EnterohemorrhagicInternational journal of molecular sciences · 2022
    Review
  13. Therapeutic Antibodies Against Shiga Toxins: Trends and Perspectives.Frontiers in cellular and infection microbiology · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gregory HallDepartment of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA. grhall@bu.edu.
Shinichiro KurosawaDepartment of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA. kurosawa@bu.edu.
Deborah J Stearns-KurosawaDepartment of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA. dstearns@bu.edu.
Boston University · US

Funding

RESEARCH TRAINING IN IMMUNOLOGYT32AI007309 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GUMMULURU, SURYARAM · 1988 to 2024
$7.4M
Development and Treatment of Pre-Clinical EHEC Models with HUSR01AI102931 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI KUROSAWA, SHINICHIRO · 2013 to 2016
$1.6M
NIAID NIH HHS R01 AI102931NIAID NIH HHS T32 AI007309
6 · The paper itself

Abstract

Ribotoxic Shiga toxins are the primary cause of hemolytic uremic syndrome (HUS) in patients infected with Shiga toxin-producing enterohemorrhagic

Indexed as

AnimalsEscherichia coli InfectionsHemolytic-Uremic SyndromeHumansRibosomesShiga-Toxigenic Escherichia coliShiga ToxinUnfolded Protein ResponseShiga Toxinhemolytic uremic syndromeribotoxic stress responseribotoxinShiga-like toxinsShiga toxinShiga toxin-producing E. coliSTECSTX1STX2unfolded protein response

Identifiers

PMID28925976
PMCPMC5618224
OpenAlexW2754541668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.