Evidence map›Paper›PMID 28925956›Full record

ArticleMolecules (Basel, Switzerland)2017

Sulfadiazine Salicylaldehyde-Based Schiff Bases: Synthesis, Antimicrobial Activity and Cytotoxicity.

Martin Krátký, Magdaléna Dzurková, Jiří Janoušek, Klára Konečná, František Trejtnar, Jiřina Stolaříková, Jarmila Vinšová

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 102 citations in OpenAlex.

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  20. A Novel Thiazolyl Schiff Base: Antibacterial and Antifungal Effects andOxidative medicine and cellular longevity · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Martin KrátkýDepartment of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic. martin.kratky@faf.cuni.cz.
Magdaléna DzurkováDepartment of Chemistry, Faculty of Science, J. E. Purkinje University, České mládeže 8, 400 96 Ústí nad Labem, Czech Republic. dzurkova.magda@seznam.cz.
Jiří JanoušekDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic. janousj2@faf.cuni.cz.
Klára KonečnáDepartment of Biological and Medical Sciences, Faculty of Pharmacy, Charles University, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic. konecna@faf.cuni.cz.
František TrejtnarDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic. trejnarf@faf.cuni.cz.
Jiřina StolaříkováLaboratory for Mycobacterial Diagnostics and Tuberculosis, Regional Institute of Public Health in Ostrava, Partyzánské námĕstí 7, 702 00 Ostrava, Czech Republic. Jirina.Stolarikova@zu.cz.
Jarmila VinšováDepartment of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic. vinsova@faf.cuni.cz.
Charles University · CZInje University · KRPublic Health Institute Ostrava · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The resistance among microbes has brought an urgent need for new drugs. Thus, we synthesized a series of Schiff bases derived from the sulfa drug sulfadiazine and various salicylaldehydes. The resulting 4-[(2-hydroxybenzylidene)amino]-

Indexed as

AldehydesAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsCell SurvivalHep G2 CellsHumansMicrobial Sensitivity TestsPyrimidinesSchiff BasesStructure-Activity RelationshipSulfadiazineAldehydesAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsPyrimidinessalicylaldehydeSchiff BasesSulfadiazineantibacterial activityantifungal activityantimycobacterial activitycytotoxicitySchiff basessulfadiazinesulfonamides

Identifiers

PMID28925956
PMCPMC6151383
OpenAlexW2754510205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.