Evidence map›Paper›PMID 28925580›Full record

Trial reportMaternal & child nutrition2018

Nutrition, hygiene, and stimulation education to improve growth, cognitive, language, and motor development among infants in Uganda: A cluster-randomized trial.

Grace K M Muhoozi, Prudence Atukunda, Lien M Diep, Robert Mwadime, Archileo N Kaaya, Anne B Skaare, Tiril Willumsen, Ane C Westerberg, Per O Iversen

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Maternal & child nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02098031 (Improving the Nutrition Status of 6 to 8 Months Old Children Through Diet Diversification and Better Dietary Intakes in the Kabale and Kisoro Districts in South-Western Uganda), which is not on this map. Cited by 48 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 13 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02098031 nacompletednot on this map

Improving the Nutrition Status of 6 to 8 Months Old Children Through Diet Diversification and Better Dietary Intakes in the Kabale and Kisoro Districts in South-Western Uganda

TypeinterventionalSponsorUniversity of OsloRan2014 to 2016Enrolled511ConditionsInfant Malnutrition, Nutrition Knowledge, Growth, Cognitive DevelopmentArmsImproving nutrition knowledge among mothers
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 13 syntheses or guidelines pooled it, 84 citations in OpenAlex.

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  4. Nutrition Education Programs Aimed at African Mothers of Infant Children: A Systematic Review.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Grace K M MuhooziDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Prudence AtukundaDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Lien M DiepOslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway.
Robert MwadimeSPRING/Uganda (USAID Project), Kampala, Uganda.
Archileo N KaayaSchool of Food Technology, Nutrition and Bioengineering, Makerere University, Kampala, Uganda.
Anne B SkaareInstitute of Clinical Dentistry, Faculty of Dentistry, University of Oslo, Oslo, Norway.
Tiril WillumsenInstitute of Clinical Dentistry, Faculty of Dentistry, University of Oslo, Oslo, Norway.
Ane C WesterbergInstitute of Health Sciences, Kristiania University College, Oslo, Norway.
Per O IversenDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.ORCID 0000-0003-2977-9153
University of Oslo · NOOslo University Hospital · NOHøyskolen Kristiania · NOMakerere University · UG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stunting is associated with impaired cognitive and motor function. The effect of an education intervention including nutrition, stimulation, sanitation, and hygiene on child growth and cognitive/language/motor development, delivered to impoverished mothers in Uganda, was assessed. In a community-based, open cluster-randomized trial, 511 mother/children dyads aged 6-8 months were enrolled to an intervention (n = 263) or control (n = 248) group. The primary outcome was change in length-for-age z-score at age 20-24 months. Secondary outcomes included anthropometry and scores on the 2 developmental scales: Bayley Scales of Infant and Toddler Development-III and the Ages and Stages Questionnaire. There was no evidence of a difference in mean length-for-age z-score at 20-24 months between the 2 study groups: 0.10, 95% CI [-0.17, 0.36], p = .49. The intervention group had higher mean composite development scores than the controls on Bayley Scales of Infant and Toddler Development-III, the mean difference being 15.6, 95% CI [10.9, 20.2], p = .0001; 9.9, 95% CI [6.4, 13.2], p = .0001; and 14.6, 95% CI [10.9, 18.2], p = .0001, for cognitive, language, and motor composite scores, respectively. The mean difference in scores from the Ages and Stages Questionnaire were 7.0, 95% CI [2.9, 11.3], p = .001; 5.9, 95% CI [1.2, 10.3], p = .01; 4.2, 95% CI [1.7, 6.7], p = .001; 8.9, 95% CI [5.3, 12.3], p = .0001; and 4.4, 95% CI [0.0, 8.8], p = .05, for communication, gross motor, fine motor, problem solving, and personal-social development, respectively. The intervention education delivered to mothers promoted early development domains in cognitive, language, and motor development but not linear growth of small children in impoverished rural communities in Uganda. Our study showed that child development may be improved with a relatively low cost intervention strategy. This trial was registered at ClinicalTrials.gov as NCT02098031.

Indexed as

Child DevelopmentChild LanguageHygieneInfant Nutritional Physiological PhenomenaChild, PreschoolCluster AnalysisCognitionFemaleHealth EducationHumansInfantInfant Nutrition DisordersMaleMotherscognitive developmentgrowthhygieneinfantnutrition educationUganda

Identifiers

PMID28925580
PMCPMC6866193
OpenAlexW2755900746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.