SynthesisCancer medicine2017
Personal use of hair dyes and risk of leukemia: a systematic literature review and meta-analysis.
Synthesis in Cancer medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Association between hair dye use and cancer in women: a systematic review and meta-analysis of case-control studies.African health sciences · 2022Pooled it
- Personal use of hair dyes and risk of leukemia: a systematic literature review and meta-analysis.Cancer medicine · 2017Pooled it
- Hepatocellular carcinoma antibodies preferably identify nitro-oxidative-DNA lesions induced by 4-Chloro-orthophenylenediamine and DEANO.Scientific reports · 2024Article
- Changing human hair fibre colour and shape from the follicle.Journal of advanced research · 2024Article
- A Comprehensive Review of Mammalian Pigmentation: Paving the Way for Innovative Hair Colour-Changing Cosmetics.Biology · 2023Review
- Risks of Leukemia in Various Industrial Groups in Korea: A Retrospective National Cohort Study.International journal of environmental research and public health · 2023Article
- Risk of Carcinogenicity Associated with Synthetic Hair Dyeing Formulations: A Biochemical View on Action Mechanisms, Genetic Variation and Prevention.Indian journal of clinical biochemistry : IJCB · 2022Review
- Hair Dye Ingredients and Potential Health Risks from Exposure to Hair Dyeing.Chemical research in toxicology · 2022Review
- Epidemiology beyond its limits.Science advances · 2022Article
- Article
- Hair Cosmetics for the Hair Loss Patient.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2021Review
- Personal use of permanent hair dyes and cancer risk and mortality in US women: prospective cohort study.BMJ (Clinical research ed.) · 2020Article
- Risk of Acute Lymphoblastic Leukemia: Results of a Case-Control Study.Asian Pacific journal of cancer prevention : APJCP · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to examine the association between personal use of hair dyes and the risk of leukemia. We conducted a systematic literature review of epidemiology studies reporting leukemia-specific cancer risks among hair dye users, and estimated the meta-relative risk (meta-RR) and corresponding 95% confidence interval (95% CI) of leukemia, comparing hair dye users to nonusers. When data from all 20 studies that met the inclusion criteria were combined, ever use of hair dye was associated with a nonstatistically significant increased risk of leukemia, meta-RR = 1.09 (95% CI: 0.97-1.22). When restricted to studies that adjusted for smoking, ever use of hair dye was not associated with leukemia, meta-RR = 0.99 (95% CI: 0.76-1.29). A statistically significant increased risk of leukemia was associated with permanent hair dye use (meta-RR = 1.19 [95% CI: 1.07-1.33]), dark hair dye use (meta-RR = 1.29 [95% CI: 1.11-1.50]), hair dye use among males (meta-RR = 1.42 [95% CI: 1.01-2.00]), hair dye use pre-1980 (meta-RR = 1.49 [95% CI: 1.21-1.83]), and hair dye use for ≥15 years (meta-RR = 1.35 [95% CI: 1.13-1.62]). Overall, findings suggest that ever use of hair dye is not a significant risk factor for leukemia. Certain hair dye use characteristics were associated with a statistically significant increased risk, but further research is required to determine whether these associations truly reflect a risk of leukemia due to methodological limitations in the underlying studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.