ArticleGlia2018
Selective knockout of astrocytic Na
Abstract read
In one paragraph
Article in Glia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 98 citations in OpenAlex.
- Role of the WNT signalling pathway in physiological and pathological blood-brain barrier.Annals of medicine · 2026Review
- Citronellal Alleviates Cognitive Impairment by Inhibiting NHE1-Mediated Mitochondrial Damage in Vascular Dementia.Applied biochemistry and biotechnology · 2026Article
- Semaglutide Mitigates Ischemic Brain Injury by Inhibiting Ferroptosis via Modulation of FoXO1 and DRP1 Pathways.Molecular neurobiology · 2025Article
- Selective Deletion of NBCe1 in Reactive Astrocytes Attenuates Ischemic Stroke Brain Damage.Glia · 2025Article
- Pharmacological inhibition of SPAK-NKCC1 complex attenuates astrogliosis and restores cerebral blood flow in a mouse model of VCID.Acta neuropathologica communications · 2025Article
- Lack of renal NHE1 exacerbates lithium-induced nephrogenic diabetes insipidus.Acta physiologica (Oxford, England) · 2025Article
- Development of Brain Permeable Drugs and Novel Strategies to Overcome the Brain Barriers for Treatment Purposes.Current pharmaceutical design · 2025Review
- Normobaric Hyperoxia Therapy in Treating Stroke.Clinical interventions in aging · 2025Review
- Upregulation of Na/H Exchanger in Astrogliosis and Early Alzheimer's Disease Pathogenesis.Aging and disease · 2024Article
- Dysregulation of Ion Channels and Transporters and Blood-Brain Barrier Dysfunction in Alzheimer's Disease and Vascular Dementia.Aging and disease · 2024Review
- pH regulating mechanisms of astrocytes: A critical component in physiology and disease of the brain.Cell calcium · 2024Review
- Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a CCL2-CCR2 pathway and NO dysregulation.Cell reports · 2024Article
- Astrocyte Regulation of Cerebral Blood Flow in Health and Disease.Cold Spring Harbor perspectives in biology · 2024Review
- SPAK inhibitor ZT-1a attenuates reactive astrogliosis and oligodendrocyte degeneration in a mouse model of vascular dementia.CNS neuroscience & therapeutics · 2024Article
- Glymphatic and lymphatic communication with systemic responses during physiological and pathological conditions in the central nervous system.Communications biology · 2024Review
- Ion transporter cascade, reactive astrogliosis and cerebrovascular diseases.Frontiers in pharmacology · 2024Review
- Inhibition of HMGB1 Attenuates Spinal Cord Edema by Reducing the Expression of NaJournal of neurotrauma · 2023Article
- Article
- Intermittent hypoxia protects against hypoxic-ischemic brain damage by inducing functional angiogenesis.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Canagliflozin, an Inhibitor of the NaCells · 2023Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 3 institutions in 1 country.
Gulnaz BegumDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0002-1509-0630
Shanshan SongDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0002-7200-5922
Shaoxia WangDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Hanshu ZhaoDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Mohammad Iqbal H BhuiyanDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Eric LiDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Rachel NepomucenoDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Qing YeDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Ming SunDepartment of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Michael Joseph CalderonDepartment of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Donna B StolzDepartment of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Claudette St CroixDepartment of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Simon C WatkinsDepartment of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Yinhuai ChenDepartment of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati, Cincinnati, Ohio.
Pingnian HeDepartment of Cellular and Molecular Physiology, Penn State Hershey College of Medicine, Hershey, Pennsylvania.
Gary E ShullDepartment of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati, Cincinnati, Ohio.
Dandan SunDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
University of Pittsburgh · USUniversity of Cincinnati · USPenn State Milton S. Hershey Medical Center · US
Funding
The Role of Na+/H+ exchanger in Cerebral IschemiaR01NS048216 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI Dandan Sun · 2005 to 2026
$6.1MCELLULAR MODULATION OF MICROVESSEL PERMEABILITY IN VIVOR01HL056237 · NHLBI · WEST VIRGINIA UNIVERSITY · PI HE, PINGNIAN · 2001 to 2013
$3.1MNitric oxide and microvessel permeability in vivoR01HL130363 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI HE, PINGNIAN · 2017 to 2020
$1.9MMicroparticles and microvascular dysfunction in diabetesR01DK097391 · NIDDK · WEST VIRGINIA UNIVERSITY · PI HE, PINGNIAN · 2013 to 2016
$1.4MRequest for a Leica 3X STED MicroscopeS10OD021540 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WATKINS, SIMON C · 2016 to 2016
$1.2MNHLBI NIH HHS R01 HL056237NHLBI NIH HHS R01 HL130363NIDDK NIH HHS R01 DK097391NIH HHS S10 OD021540NINDS NIH HHS R01 NS048216
Abstract
Stimulation of Na
Indexed as
AnimalsAstrocytesBlood-Brain BarrierBrain InfarctionCerebrovascular CirculationDisease Models, AnimalGene Expression RegulationGlial Fibrillary Acidic ProteinGliosisInfarction, Middle Cerebral ArteryMaleMatrix Metalloproteinase 9MiceMice, Inbred C57BLMice, TransgenicMicroscopy, Electron, TransmissionGlial Fibrillary Acidic ProteinMatrix Metalloproteinase 9Mmp9 protein, mouseSlc9a1 protein, mouseSodium-Hydrogen Exchanger 1astrocyte end-feetblood-brain barriercerebral edemagliosisMMPneurovascular unit
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.