ArticleLa Radiologia medica2018
Evaluation of deep myometrial invasion in endometrial cancer patients: is dual-energy CT an option?
Article in La Radiologia medica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Practical applications of photon-counting CT in oncology: an organ-based pictorial review.Insights into imaging · 2026Article
- Diagnostic Imaging Performance of Dual-Energy Computed Tomography Compared with Conventional Computed Tomography and Magnetic Resonance Imaging for Uterine Cervical Cancer.The Indian journal of radiology & imaging · 2024Article
- Preliminary Experience with Virtual Monoenergetic Imaging and Iodine Mapping in the Primary Staging of Endometrial Cancer.Cancers · 2024Article
- Comparison of preoperative diagnostic performance between dual-energy CT, conventional CT, and MRI in endometrial cancer.Polish journal of radiology · 2024Article
- Radiomics-based fertility-sparing treatment in endometrial carcinoma: a review.Insights into imaging · 2023Review
- Diagnostic accuracy of MRI for evaluating myometrial invasion in endometrial cancer: a comparison of MUSE-DWI, rFOV-DWI, and DCE-MRI.La Radiologia medica · 2023Article
- COMPARISON OF TVUS, MRI, AND FROZEN SECTION METHODS IN PREOPERATIVE DETECTION OF MYOMETRIAL INVASION IN PATIENTS WITH ENDOMETRIAL CANCER.Acta clinica Croatica · 2021Article
- Spectral CT of the abdomen: Where are we now?Insights into imaging · 2021Review
- Multimodality advanced imaging and intervention in gland diseases.Gland surgery · 2020Article
- Dual-energy CT: theoretical principles and clinical applications.La Radiologia medica · 2019Review
- Third-generation dual-source dual-energy CT in pediatric congenital heart disease patients: state-of-the-art.La Radiologia medica · 2019Review
- Endometrial cancer: an overview of novelties in treatment and related imaging keypoints for local staging.Cancer imaging : the official publication of the International Cancer Imaging Society · 2018Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAssessment of deep (>50%) myometrial invasion by dual-energy CT (DECT) and Trans-Vaginal US (TVUS) in patients with endometrial cancer.
methodsWe retrospectively enrolled patients with endometrial cancer who underwent DECT and TVUS for pre-surgical staging. Three sets of images were evaluated: 70 keV (routine CT images), 50 keV, and iodine-water reconstructions. The gold standard was pathology after surgery. The agreement between the different imaging modalities and the gold standard was estimated. Sensitivity, specificity and accuracy for each imaging modality were evaluated with 95% confidence intervals (CI).
resultsThirty-nine patients were included. Median time from CT and TVUS to surgery was 23 and 18 days, respectively. The best agreement between evaluation of myometrial infiltration and the gold standard was 0.88 (0.72, 1.00) for the 50 keV images; the worst agreement was 0.43 (0.00, 0.88) for the 70 keV images. CT iodine reconstructions and US agreement were comparable. Specificity, sensitivity and accuracy were 0.91, 1.00, 0.94; 0.57, 0.86, 0.71; 0.82, 1.00, 0.87; 0.91, 0.77, 0.86 for 50 keV, 70 keV, iodine reconstructions and ultrasound, respectively.
conclusionsDECT is a promising tool for assessment of myometrial invasion in endometrial cancer patients, with a special focus on 50 keV images.
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