Evidence map›Paper›PMID 28924729›Full record

Trial reportJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2018

Dor Vs Toupet Fundoplication After Laparoscopic Heller Myotomy: Long-Term Randomized Controlled Trial Evaluated by High-Resolution Manometry.

Gonzalo Torres-Villalobos, Enrique Coss-Adame, Janette Furuzawa-Carballeda, Fernanda Romero-Hernández, Blanca Blancas-Breña, Samuel Torres-Landa, Axel Palacios-Ramírez, Edgar Alejandro-Medrano, Axel Hernández-Ávila, Athenea Flores-Najera and 4 more

Abstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Fundoplication in laparoscopic Heller's cardiomyotomy for achalasia.The Cochrane database of systematic reviews · 2022
    Pooled it
  3. Pooled it
  4. Pooled it
  5. High-Resolution Manometry in Treated Achalasia: Scoping Review and Novel Nomenclature.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Surgical management of achalasia.Abdominal radiology (New York) · 2025
    Review
  11. Article
  12. Article
  13. Modern Achalasia: Diagnosis, Classification, and Treatment.Journal of neurogastroenterology and motility · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Achalasia.Nature reviews. Disease primers · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Gonzalo Torres-VillalobosDepartment of Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico. torresvgm@yahoo.com.mx.
Enrique Coss-AdameDepartment of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico.
Janette Furuzawa-CarballedaDepartment of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico.
Fernanda Romero-HernándezDepartment of Experimental Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico.
Blanca Blancas-BreñaDepartment of Experimental Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico.
Samuel Torres-LandaDepartment of Experimental Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico.
Axel Palacios-RamírezDepartment of Experimental Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico.
Edgar Alejandro-MedranoDepartment of Experimental Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico.
Axel Hernández-ÁvilaDepartment of Experimental Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico.
Athenea Flores-NajeraDepartment of Experimental Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico.
Lourdes Margarita Ávila EscobedoDepartment of Radiology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico.
Cecilia Ramírez AnguloDepartment of Experimental Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico.
Angélica Rodríguez-GarcésDepartment of Experimental Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico.
Miguel Ángel ValdovinosDepartment of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col Belisario Domínguez, Sección XVI, Alcaldía Tlalpan, 14080, Mexico City, Mexico.
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic Heller myotomy (LHM) with partial fundoplication is an effective treatment for achalasia. However, the type of fundoplication is still a subject of debate.

aimThe aim of the study is to identify which partial fundoplication leads to better control of acid exposure, manometric parameters, and symptoms scores.

methodsA randomized controlled trial was performed to compare Dor vs Toupet fundoplication after LHM. The preoperative diagnosis was made by high-resolution manometry (HRM), upper endoscopy, and barium esophagogram. Preoperative and postoperative symptoms were evaluated with Eckardt, GERD-HRQL, and EAT-10 questionnaires.

resultsSeventy-three patients were randomized, 38 underwent Dor and 35 Toupet. Baseline characteristics were similar between groups. Postoperative HRM showed that the integrated relaxation pressure (IRP) and basal lower esophageal sphincter (LES) pressure were similar at 6 and 24 months. The number of patients with abnormal acid exposure was significantly lower for Dor (6.9%) than that of Toupet (34.0%) at 6 months, but it was not different at 12 or 24 months. No differences were found in postoperative symptom scores at 1, 6, or 24 months.

conclusionThere were no differences in symptom scores or HRM between fundoplications in the long term. A higher percentage of abnormal 24-h pH test were found for the Toupet group, with no difference in the long term.

Indexed as

Heller MyotomyAdolescentAdultAgedEsophageal AchalasiaEsophageal pH MonitoringEsophageal Sphincter, LowerEsophagoscopyFemaleFundoplicationHumansHydrogen-Ion ConcentrationLaparoscopyMaleManometryMiddle AgedAchalasiaDorFundoplicationLaparoscopic Heller myotomyToupet

Identifiers

PMID28924729
OpenAlexW2753968838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.