Evidence map›Paper›PMID 28924723›Full record

ArticleClinical rheumatology2018

Sixteen Chinese pediatric brucellosis patients onset of fever in non-epidemic areas and 8 developed with osteoarticular involvement.

Xinning Wang, Yuchun Yan, Fengqi Wu, Gaixiu Su, Shengnan Li, Xinyu Yuan, Jianming Lai, Zhixuan Zhou

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Reactivation of hidden-latentAntimicrobial agents and chemotherapy · 2025
    Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Laboratory Diagnosis of Human Brucellosis.Clinical microbiology reviews · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xinning WangDepartment of Pediatric Rheumatology and Immunology, Children's Hospital affiliated to Capital Institute of Pediatrics, Yabao Road No 2, Chaoyang district, Beijing, 10020, China.
Yuchun YanDepartment of Radiology, Children's Hospital affiliated to Capital Institute of Pediatrics, Yabao Road No 2, Chaoyang district, Beijing, 10020, China.
Fengqi WuDepartment of Pediatric Rheumatology and Immunology, Children's Hospital affiliated to Capital Institute of Pediatrics, Yabao Road No 2, Chaoyang district, Beijing, 10020, China.
Gaixiu SuDepartment of Pediatric Rheumatology and Immunology, Children's Hospital affiliated to Capital Institute of Pediatrics, Yabao Road No 2, Chaoyang district, Beijing, 10020, China.
Shengnan LiDepartment of Pediatric Rheumatology and Immunology, Children's Hospital affiliated to Capital Institute of Pediatrics, Yabao Road No 2, Chaoyang district, Beijing, 10020, China.
Xinyu YuanDepartment of Radiology, Children's Hospital affiliated to Capital Institute of Pediatrics, Yabao Road No 2, Chaoyang district, Beijing, 10020, China.
Jianming LaiDepartment of Pediatric Rheumatology and Immunology, Children's Hospital affiliated to Capital Institute of Pediatrics, Yabao Road No 2, Chaoyang district, Beijing, 10020, China. laijm99@sina.com.
Zhixuan ZhouDepartment of Pediatric Rheumatology and Immunology, Children's Hospital affiliated to Capital Institute of Pediatrics, Yabao Road No 2, Chaoyang district, Beijing, 10020, China. zhouzhixuan9@sina.com.
Children's Hospital of Capital Institute of Pediatrics · CNCapital Institute of Pediatrics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study is to summarize the manifestations, diagnosis, differential diagnosis, and treatment of childhood brucellosis in non-epidemic areas of China. A retrospective review of 16 admitted children patients with brucella's disease who were diagnosed of brucellosis during the period from 2011 to 2016 was performed. Diagnostic criteria, clinical presentations, and outcomes were recorded. The most common symptom was fever. Osteoarticular involvement was found in 50% of the patients. They were infected by contacting with infected animals or consuming of unpasteurized milk or meat of sheep or goats, also. Standard agglutination test was positive in all patients and blood culture in 10 (62.5%) patients as well as medulloculture in 3 (18.8%) patients were positive. A combination of antibiotic treatment with rifampin plus cotrimoxazole showed good response and all clinical manifestations improved. Brucellosis is misdiagnosed frequently and should be considered in the differential diagnosis when patients do not respond to standard treatment. Blood culture, together with brucella serology test, is important and helpful in the diagnosis. MRI is a good method in differentiating those with symptoms of arthritis.

Indexed as

AdolescentAgglutination TestsAnti-Bacterial AgentsBrucellosisChildChild, PreschoolChinaDiagnosis, DifferentialFemaleFeverHumansInfantMaleRetrospective StudiesRifampinTreatment OutcomeAnti-Bacterial AgentsRifampinTrimethoprim, Sulfamethoxazole Drug CombinationBrucellaChinese childrenMagnetic resonanceMisdiagnoseOsteoarticular

Identifiers

PMID28924723
OpenAlexW2754939659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.