Evidence map›Paper›PMID 28924696›Full record

ArticleEJNMMI physics2017

Guidelines for quality control of PET/CT scans in a multicenter clinical study.

Ivalina Hristova, Ronald Boellaard, Paul Galette, Lalitha K Shankar, Yan Liu, Sigrid Stroobants, Otto S Hoekstra, Wim J G Oyen

Abstract read
In one paragraph

Article in EJNMMI physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ivalina HristovaDepartment of Nuclear Medicine, Radboud University Medical Centre, Geert Grooteplein-Zuid 10, 6525 GA, Nijmegen, The Netherlands. ivalinahr@gmail.com.
Ronald BoellaardUniversity Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Paul GaletteGSK, Experimental Medicine Imaging, Upper Providence, PA, USA.
Lalitha K ShankarDivision of Cancer Treatment and Diagnosis National Cancer Institute, Bethesda, MD, USA.
Yan LiuEuropean Organization for Research and Treatment of Cancer, Imaging Group, Brussels, Belgium.
Sigrid StroobantsEuropean Organization for Research and Treatment of Cancer, Imaging Group, Brussels, Belgium.
Otto S HoekstraEuropean Organization for Research and Treatment of Cancer, Imaging Group, Brussels, Belgium.
Wim J G OyenDepartment of Nuclear Medicine, Radboud University Medical Centre, Geert Grooteplein-Zuid 10, 6525 GA, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To date, there is no published detailed checklist with parameters referencing the DICOM tag information with respect to the quality control (QC) of PET/CT scans. The aims of these guidelines are to provide the know-how for effectively controlling the quality of PET/CT scans in multicenter studies, to standardize the QC, to give sponsors and regulatory agencies a basis for justification of the data quality when using standardized uptake values as an imaging biomarker, to document the compliance with the imaging guidelines, to verify the per protocol population versus intent to treat population, and to safeguard the validity of multicenter study conclusions employing standardized uptake value (SUV) as an imaging biomarker which is paramount to the scientific community. Following the proposed guidelines will ensure standardized prospective imaging QC of scans applicable to most studies where SUVs are used as an imaging biomarker. The multitude of factors affecting SUV measurements when not controlled inflicts noise on the data. Decisions on patient management with substantial noise would be devastating to patients, ultimately undermine treatment outcome, and invalidate the utility of SUV as an imaging biomarker usefulness. Strict control of the data quality used for the validation of SUV as an imaging biomarker would ensure trust and reliability of the data.

Identifiers

PMID28924696
PMCPMC5603471

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.