Evidence map›Paper›PMID 28924616›Full record

ArticleParasite epidemiology and control2017

Soil transmitted helminth infections are not associated with compromised antibody responses to previously administered measles and tetanus vaccines among HIV-1 infected, ART naïve Kenyan adults.

Helen L Storey, Benson Singa, Jackie Naulikha, Helen Horton, Barbra A Richardson, Grace John-Stewart, Judd L Walson

Open access · goldAbstract read
In one paragraph

Article in Parasite epidemiology and control, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Immunological Considerations forFrontiers in immunology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Helen L StoreyDepartment of Epidemiology, University of Washington, 325 9th Ave, Seattle, WA 98104 USA.
Benson SingaKenya Medical Research Institute, Mbagathi Rd, Nairobi, Kenya.
Jackie NaulikhaKenya Medical Research Institute, Mbagathi Rd, Nairobi, Kenya.
Helen HortonSeattle Biomedical Research Institute, 307 Westlake Ave N #500, Seattle, WA, USA.
Barbra A RichardsonDepartment of Biostatistics, University of Washington, 325 9th Ave, Seattle, WA 98104 USA.
Grace John-StewartDepartment of Epidemiology, University of Washington, 325 9th Ave, Seattle, WA 98104 USA.
Judd L WalsonDepartment of Epidemiology, University of Washington, 325 9th Ave, Seattle, WA 98104 USA.
University of Washington · USKenya Medical Research Institute · KECenter for Infectious Disease Research · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
NRSA Training CoreTL1TR002318 · NCATS · UNIVERSITY OF WASHINGTON · PI Megan Moore · 2017 to 2026
$8.4M
Multiplex Serodiagnostic Protein MicroarrayU01AI078213 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI FELGNER, PHILIP LOUIS · 2008 to 2012
$3.7M
Institute for Translational Health Science (TL1)TL1RR025016 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$2.7M
NCATS NIH HHS TL1 TR002318NCRR NIH HHS TL1 RR025016NIAID NIH HHS P30 AI027757NIAID NIH HHS U01 AI078213
6 · The paper itself

Abstract

In many regions of sub-Saharan Africa, both HIV and helminth infections are prevalent. HIV-1 (human immunodeficiency virus type 1) and helminth infections can both compromise immune responses in humans. To determine whether the presence of helminth infection or the treatment of helminth infection alters unstimulated vaccine responses among HIV-1 infected individuals, we conducted two nested serologic studies. Blood samples were collected for HIV disease monitoring and vaccine-specific serologic assays, while stool was evaluated by direct microscopy methods. We compared antibody responses to measles and tetanus vaccines in helminth-infected (

Indexed as

coinfectionHIVimmunizationsoil-transmitted helminthvaccine preventable disease

Identifiers

PMID28924616
PMCPMC5600515
OpenAlexW2570916840

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.