Evidence map›Paper›PMID 28924581›Full record

ArticleData in brief2017

Data on the effects of eIF6 downmodulation on the proportions of innate and adaptive immune system cell subpopulations and on thymocyte maturation.

Nicola Manfrini, Sara Ricciardi, Annarita Miluzio, Maya Fedeli, Alessandra Scagliola, Simone Gallo, Thure Adler, Dirk H Busch, Valerie Gailus-Durner, Helmut Fuchs and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nicola ManfriniNational Institute of Molecular Genetics "Romeo ed Enrica Invernizzi" - INGM, via F. Sforza 35, 20122 Milan, Italy.
Sara RicciardiNational Institute of Molecular Genetics "Romeo ed Enrica Invernizzi" - INGM, via F. Sforza 35, 20122 Milan, Italy.
Annarita MiluzioNational Institute of Molecular Genetics "Romeo ed Enrica Invernizzi" - INGM, via F. Sforza 35, 20122 Milan, Italy.
Maya FedeliExperimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, DIBIT, H. San Raffaele Scientific Institute, via Olgettina 58, 20132 Milan, Italy.
Alessandra ScagliolaNational Institute of Molecular Genetics "Romeo ed Enrica Invernizzi" - INGM, via F. Sforza 35, 20122 Milan, Italy.
Simone GalloNational Institute of Molecular Genetics "Romeo ed Enrica Invernizzi" - INGM, via F. Sforza 35, 20122 Milan, Italy.
Thure AdlerGerman Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.
Dirk H BuschInstitute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Trogerstrasse 30, 81675 Munich, Germany.
Valerie Gailus-DurnerGerman Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.
Helmut FuchsGerman Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.
Martin Hrabě de AngelisGerman Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.
Stefano BiffoNational Institute of Molecular Genetics "Romeo ed Enrica Invernizzi" - INGM, via F. Sforza 35, 20122 Milan, Italy.

Funding

European Research Council 338999
6 · The paper itself

Abstract

The data described in this article are related to "High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4

Indexed as

Adaptive immunityeIF6Immune systemInnate immunityThymocyte

Identifiers

PMID28924581
PMCPMC5591389

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.