Evidence map›Paper›PMID 28924553›Full record

ArticleActa pharmaceutica Sinica. B2017

Amino-functionalized poloxamer 407 with both mucoadhesive and thermosensitive properties: preparation, characterization and application in a vaginal drug delivery system.

Liqian Ci, Zhigang Huang, Yu Liu, Zhepeng Liu, Gang Wei, Weiyue Lu

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 78 citations in OpenAlex.

  1. Design-ExpertPharmaceutics · 2026
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  18. Autoclaving of Poloxamer 407 hydrogel and its use as a drug delivery vehicle.Journal of biomedical materials research. Part B, Applied biomaterials · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Liqian CiSchool of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
Zhigang HuangSchool of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
Yu LiuDepartment of Pharmaceutics, School of Pharmacy, Fudan University & Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education, Shanghai 201203, China.
Zhepeng LiuSchool of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
Gang WeiDepartment of Pharmaceutics, School of Pharmacy, Fudan University & Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education, Shanghai 201203, China.
Weiyue LuDepartment of Pharmaceutics, School of Pharmacy, Fudan University & Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education, Shanghai 201203, China.
Fudan University · CNUniversity of Shanghai for Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lack of mucoadhesive properties is the major drawback to poloxamer 407 (F127)-based

Indexed as

Acetate gossypolACN, anhydrous acetonitrileAG, acetate gossypolAG-loaded FG, F127 gel-loaded with acetate gossypolAG-loaded NFG, F127-NH2 gel-loaded with acetate gossypolAmino groupANOVA, one-way analysis of varianceC6, 6-coumarinCDI, carbonyl diimidazoleCMC, critical micelle concentrationDAPI, 2-(4-amidinophenyl)-6-indolecarbamindine dihydrochlorideDiR, 1,1ʹ-dioctadecyl-3,3,3ʹ,3ʹ-tetramethylindotricarbocyanine iodideDLS, dynamic light scatteringDPH, 1,6-diphenyl-1,3,5-hexatrieneDTT, dithiothreitolEDTA, ethylenediamine tetraacetic acidEMS, endometriosisF127, Pluronic F127FG, F127 gelFTIR, Fourier transform infraredH&E, hematoxylin and eosinICR, Institute of Cancer ResearchIn situ hydrogelMucoadhesive gelNF, amino-functionalised poloxamer 407NFG, aminated poloxamer 407-based temperature sensitive hydrogelNMR, nuclear magnetic resonanceOCT, optical coherence tomographyPBS, phosphate buffered salinePDI, polydispersity indexPEO, poly(ethylene oxide)PGM, porcine gastric mucinPoloxamer 407PPO, poly(propylene oxide)TEM, transmission electron microscopyVFS, vaginal fluid stimulant

Identifiers

PMID28924553
PMCPMC5595263
OpenAlexW2611818005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.