Evidence map›Paper›PMID 28924363›Full record

ArticleInternational journal of medical sciences2017

Thrombospondin-1 Gene Deficiency Worsens the Neurological Outcomes of Traumatic Brain Injury in Mice.

Chongjie Cheng, Zhanyang Yu, Song Zhao, Zhengbu Liao, Changhong Xing, Yinghua Jiang, Yong-Guang Yang, Michael J Whalen, Eng H Lo, Xiaochuan Sun and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Diagnostic and prognostic utility of plasma thrombospondin-1 levels in traumatic brain injury.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. The Role of BDNF in Experimental and Clinical Traumatic Brain Injury.International journal of molecular sciences · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Chongjie ChengDepartment of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhanyang YuNeuroprotection Research Laboratory, Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Song ZhaoDepartments of Orthopedic and Neurosurgery, The First Bethune Hospital of Jilin University, Changchun, Jilin, China.
Zhengbu LiaoDepartment of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Changhong XingNeuroprotection Research Laboratory, Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Yinghua JiangDepartment of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yong-Guang YangColumbia Center for Translational Immunology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Michael J WhalenDepartment of Pediatrics, Pediatric Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Eng H LoNeuroprotection Research Laboratory, Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Xiaochuan SunDepartment of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiaoying WangNeuroprotection Research Laboratory, Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Harvard University · USFirst Affiliated Hospital of Chongqing Medical University · CNChongqing Medical University · CNColumbia University · USFirst Bethune Hospital of Jilin University · CNMassachusetts General Hospital · US

Funding

Role of CD47 in xenograft rejection by macrophagesR01AI064569 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI YANG, YONG-GUANG · 2008 to 2016
$3.1M
NIAID NIH HHS R01 AI064569
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Angiopoietin-1AnimalsBiomarkersBlood-Brain BarrierBrain-Derived Neurotrophic FactorBrain InjuriesCerebral CortexCognitionDisease Models, AnimalMaze LearningMiceMice, Inbred C57BLMice, KnockoutNeovascularization, PhysiologicRecovery of FunctionSynaptophysinAngiopoietin-1Angpt1 protein, mouseBiomarkersBrain-Derived Neurotrophic FactorSynaptophysinSyp protein, mouseThbs1 protein, mouseThrombospondin 1Vascular Endothelial Growth Factor Avascular endothelial growth factor A, mouseangiogenesisblood-brain-barriermorris water maze (MWM)neurological severity score (NSS)synaptogenesis.Thromspondin-1 (TSP-1)traumatic brain injury

Identifiers

PMID28924363
PMCPMC5599915
OpenAlexW2741362367

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.