Evidence map›Paper›PMID 28924349›Full record

ArticleInternational journal of nanomedicine2017

Autophagy promotes degradation of polyethyleneimine-alginate nanoparticles in endothelial progenitor cells.

Guo-Dong Wang, Yu-Zhen Tan, Hai-Jie Wang, Pei Zhou

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Genetic Delivery and Gene Therapy in Pulmonary Hypertension.International journal of molecular sciences · 2021
    Review
  4. Review
  5. Cationic Nanostructures for Vaccines Design.Biomimetics (Basel, Switzerland) · 2020
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Guo-Dong WangDepartment of Anatomy, Histology and Embryology, Shanghai Medical School of Fudan University, Shanghai, China.
Yu-Zhen TanDepartment of Anatomy, Histology and Embryology, Shanghai Medical School of Fudan University, Shanghai, China.
Hai-Jie WangDepartment of Anatomy, Histology and Embryology, Shanghai Medical School of Fudan University, Shanghai, China.
Pei ZhouDepartment of Anatomy, Histology and Embryology, Shanghai Medical School of Fudan University, Shanghai, China.
Shanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyethyleneimine (PEI)-alginate (Alg) nanoparticle (NP) is a safe and effective vector for delivery of siRNA or DNA. Recent studies suggest that autophagy is related to cytotoxicity of PEI NPs. However, contribution of autophagy to degradation of PEI-Alg NPs remains unknown. CD34

Indexed as

AutophagyAlginatesAnimalsApoptosisBeclin-1Endothelial Progenitor CellsGlucuronic AcidHexuronic AcidsLysosomesMicrotubule-Associated ProteinsMitochondriaNanoparticlesPolyethyleneimineRats, Sprague-DawleyReactive Oxygen SpeciesVascular Endothelial Growth Factor Receptor-3AlginatesAnxa3 protein, ratBeclin-1Glucuronic AcidHexuronic AcidsMicrotubule-Associated ProteinsPolyethyleneimineReactive Oxygen SpeciesVascular Endothelial Growth Factor Receptor-3alginateautophagyendothelial progenitor cellsnanoparticlespolyethyleneimine

Identifiers

PMID28924349
PMCPMC5595362
OpenAlexW2751012052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.