Evidence map›Paper›PMID 28924348›Full record

ArticleInternational journal of nanomedicine2017

Single-walled carbon nanotubes-ciprofloxacin nanoantibiotic: strategy to improve ciprofloxacin antibacterial activity.

Mohyeddin Assali, Abdel Naser Zaid, Farah Abdallah, Motasem Almasri, Rasha Khayyat

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  8. Development ofBioMed research international · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohyeddin AssaliDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An Najah National University, Nablus, Palestine.
Abdel Naser ZaidDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An Najah National University, Nablus, Palestine.
Farah AbdallahDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An Najah National University, Nablus, Palestine.
Motasem AlmasriDepartment of Biology and Biotechnology, Faculty of Science, An Najah National University, Nablus, Palestine.
Rasha KhayyatDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An Najah National University, Nablus, Palestine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As infectious diseases continue to be one of the greatest health challenges worldwide, the demand toward alternative agents is continuously increasing. Recent advancement in nanotechnology has expanded our ability to design and construct nanomaterials to treat bacterial infections. Carbon nanotubes are one among these nanomaterials. Herein, we describe the covalent functionalization of the single-walled carbon nanotubes (SWCNTs) with multiple molecules of ciprofloxacin. The prepared nanoantibiotics were characterized using different techniques, including transmission electron microscopy, Raman spectroscopy, and thermogravimetric analysis. The characterization of the nanoantibiotics confirmed the successful covalent functionalization of the SWCNTs with 55% of functionalization as has been observed by thermogravimetric analysis. The release profile revealed that 90% of the loaded ciprofloxacin was released within 2.5 h at pH 7.4 showing a first-order release profile with

Indexed as

Anti-Bacterial AgentsCiprofloxacinEscherichia coliHeLa CellsHumansMicrobial Sensitivity TestsMicroscopy, Electron, TransmissionNanotechnologyNanotubes, CarbonPseudomonas aeruginosaSpectrum Analysis, RamanStaphylococcus aureusThermogravimetryAnti-Bacterial AgentsCiprofloxacinNanotubes, Carboncarbon nanotubescovalent functionalizationhydrophilic/hydrophobic balancenanoantibiotic

Identifiers

PMID28924348
PMCPMC5595360

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.