Evidence map›Paper›PMID 28924346›Full record

ArticleInternational journal of nanomedicine2017

Co-delivery of polyinosinic:polycytidylic acid and flagellin by poly(lactic-

Xiaojing Dai, Jintian He, Ruxia Zhang, Guanghao Wu, Fangfang Xiong, Baohua Zhao

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaojing DaiCollege of Life Science, Hebei Normal University, Shijiazhuang City, Hebei Province, People's Republic of China.
Jintian HeCollege of Life Science, Hebei Normal University, Shijiazhuang City, Hebei Province, People's Republic of China.
Ruxia ZhangCollege of Life Science, Hebei Normal University, Shijiazhuang City, Hebei Province, People's Republic of China.
Guanghao WuCollege of Life Science, Hebei Normal University, Shijiazhuang City, Hebei Province, People's Republic of China.
Fangfang XiongCollege of Life Science, Hebei Normal University, Shijiazhuang City, Hebei Province, People's Republic of China.
Baohua ZhaoCollege of Life Science, Hebei Normal University, Shijiazhuang City, Hebei Province, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present work was to investigate the synergistic effect between toll-like receptor (TLR) 3 ligand polyinosinic:polycytidylic acid (pI:C) and TLR5 ligand flagellin (FLN) on immune responses induced by nasally delivered hepatitis B virus surface antigen (HBsAg). Mannan and chitosan oligosaccharide-modified, pH-responsive poly(lactic-

Indexed as

Administration, IntranasalAnimalsChitosanDrug CarriersDrug SynergismFemaleFlagellinHepatitis B Surface AntigensInterferon-gammaInterleukin-10Interleukin-12Lactic AcidMacrophagesMicrospheresPolyglycolic AcidPoly I-CChitosanDrug CarriersFlagellinHepatitis B Surface AntigensInterferon-gammaInterleukin-10Interleukin-12Lactic AcidPolyglycolic AcidPoly I-CPolylactic Acid-Polyglycolic Acid Copolymerflagellinhepatitis B surface antigenintranasal vaccinationPLGA MPspolyinosinic:polycytidylic acidtoll-like receptor

Identifiers

PMID28924346
PMCPMC5595363

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.