ArticleClinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association2017
Childhood Adversities and Depression in Adulthood: Current Findings and Future Directions.
Article in Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
62 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- A Systematic Review and Meta-Analysis of the Association Between Childhood Maltreatment and Adult Depression.Acta psychiatrica Scandinavica · 2025Pooled it
- Assessment of suicidal thoughts and behaviors in adults: A systematic review of measure psychometric properties and implications for clinical and research utility.Clinical psychology review · 2024Pooled it
- Child maltreatment and depression: A meta-analysis of studies using the Childhood Trauma Questionnaire.Child abuse & neglect · 2020Pooled it
- Psychological Mediators of the Association Between Childhood Emotional Abuse and Depression: A Systematic Review.Frontiers in psychiatry · 2020Pooled it
- Childhood Maltreatment and Impulsivity: A Meta-Analysis and Recommendations for Future Study.Journal of abnormal child psychology · 2019Pooled it
- Childhood maltreatment and non-suicidal self-injury: a systematic review and meta-analysis.The lancet. Psychiatry · 2018Pooled it
- Linking childhood emotional abuse and depressive symptoms: The role of emotion dysregulation and interpersonal problems.PloS one · 2019Trial
- The correlations between psychotic symptoms and childhood maltreatment as well as sex differences in adolescents with major depressive disorder.European archives of psychiatry and clinical neuroscience · 2026Article
- Childhood Trauma and Aggression: The Role of Epistemic Trust.Journal of child & adolescent trauma · 2026Article
- Lifetime adversity exposure, mood symptoms, and immune mitochondrial bioenergetics.medRxiv : the preprint server for health sciences · 2026Article
- Prefrontal Cortex Dysfunction as a Precipitating Factor for Schizophrenia and Depression.Journal of neurochemistry · 2026Review
- From trauma exposure to depression or resilience: cognitive-emotional vulnerabilities and protective roles of rumination, emotion dysregulation, and self-compassion.Frontiers in psychiatry · 2026Review
- The Impact of Childhood Household Violence on HIV-Related Outcomes in People With HIV in the United States: The Role of Psychological Distress and Social Stressors.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- Harsh parenting in adolescence and symptoms of depression in emerging adulthood: The moderating role of sleep.Sleep health · 2025Article
- Adverse childhood experiences and depressive symptoms across adolescence and adulthood: A latent class analysis and time-varying effect model.Child abuse & neglect · 2025Article
- Childhood adversity and racial discrimination forecast suicidal and death ideation among emerging adult Black men: A longitudinal analysis.Cultural diversity & ethnic minority psychology · 2025Article
- Five hypothesized biological mechanisms linking adverse childhood experiences with anxiety, depression, and PTSD: A scoping review.Neuroscience and biobehavioral reviews · 2025Article
- Childhood socio-economic disadvantages versus adverse care experiences: Mediation and moderation impacts on late-life depressive symptoms.European psychiatry : the journal of the Association of European Psychiatrists · 2024Article
- Childhood adversity trajectories and weight status in young adult men: a register-based study including 359,783 Danish men.International journal of obesity (2005) · 2024Article
- Impact of Childhood Maltreatment on Cognitive Function and Its Relationship With Emotion Regulation in Young Adults.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2024Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Considerable support exists supporting a relationship between childhood adversities and adult depression. Consistent evidence has emerged linking early life adversities with a more chronic course for depression, as well as to poorer treatment outcomes. What remain decidedly less clear, however, are the moderators and mediating mechanisms underlying this association. This article provides a review of the existing research relating early adversities to adult depression, as well as recent studies suggestive of potential mediators and moderators of this relation. Advances in these areas are important for their potential to lead to the identification of new targets for clinical intervention for adults with a history of childhood adversities, as well as to the development of individually tailored prevention and treatment strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.