ArticleNature microbiology2017
Metabolic crosstalk regulates Porphyromonas gingivalis colonization and virulence during oral polymicrobial infection.
Open access · greenAbstract read
In one paragraph
Article in Nature microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 1 pooled it
10.1field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
93 citing papers in PubMed, 1 synthesis or guideline pooled it, 139 citations in OpenAlex.
- Thermosensitive Hydrogels for Periodontal Regeneration: A Systematic Review of the Evidence.Clinical and experimental dental research · 2024Pooled it
- Oral microbiome modulation mitigates hyperglycemia exacerbation in gestational diabetes mellitus.Nature communications · 2026Trial
- Trial
- Decoding strain level interactions betweenVirulence · 2026Article
- Polymicrobial-driven NLRP6 inflammasome regulates IL-1β production and alveolar bone loss in a murine model of periodontitis.PLoS pathogens · 2026Article
- Cross-site oral and esophageal microbiome signatures define diagnostic patterns and reveal mechanistic drivers of ESCC.iScience · 2026Article
- Multi-Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Neutrophil Activation Decreases Ability to Kill Oral Streptococcus gordonii.Molecular oral microbiology · 2026Article
- Influence of E-Liquids and Oral Commensal Bacteria on the Growth ofDentistry journal · 2026Article
- Non-peptide dysbiosis metabolites reprogram a peptide quorum-sensing receptor to induce sustained predation in beneficial streptococci.PLoS biology · 2026Article
- Supragingival Biomarker flora of Children With and Without Cariogenic Disease and Black Stains, Aged 3 to 6 Years.International dental journal · 2026Article
- Article
- Oral microbiome contribution in colorectal carcinogenesis: polymicrobial interactions and virulence determinants.Frontiers in cellular and infection microbiology · 2026Review
- The Oral-Brain Axis in Alzheimer's Disease: From Microbial Dysbiosis to Neurodegeneration.Microorganisms · 2025Review
- Tyrosine phosphorylation coupling of one-carbon metabolism and virulence in an endogenous pathogen.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The impact of vaping behavior on functional changes within the subgingival microbiome.Scientific reports · 2025Article
- Integrative microbiome- and metatranscriptome-based analyses reveal diagnostic biomarkers for peri-implantitis.NPJ biofilms and microbiomes · 2025Article
- PorA of the Type IX Secretion Is a Ligand of the PorXY Two-Component Regulatory System in Porphyromonas gingivalis.Molecular microbiology · 2025Article
- Regulating periodontal disease with smart stimuli-responsive systems: Antimicrobial activity, immunomodulation, periodontium regeneration.Materials today. Bio · 2025Review
- The role of salivary metabolomics in chronic periodontitis: bridging oral and systemic diseases.Metabolomics : Official journal of the Metabolomic Society · 2025Review
33 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 5 institutions in 2 countries.
Masae KuboniwaDepartment of Preventive Dentistry, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka, 565-0871, Japan.
John R HouserInstitute for Cellular and Molecular Biology, and Center for Systems and Synthetic Biology, The University of Texas at Austin, Austin, TX, 78712, USA.
Erik L HendricksonCenter for Microbial Proteomics and Chemical Engineering, University of Washington, Seattle, WA, 98195, USA.
Qian WangDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, 40292, USA.
Samar A AlghamdiDepartment of Preventive Dentistry, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Akito SakanakaDepartment of Preventive Dentistry, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka, 565-0871, Japan.ORCID http://orcid.org/0000-0001-9733-6886
Daniel P MillerDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, 40292, USA.
Justin A HutchersonDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, 40292, USA.
Tiansong WangCenter for Microbial Proteomics and Chemical Engineering, University of Washington, Seattle, WA, 98195, USA.
David A C BeckCenter for Microbial Proteomics and Chemical Engineering, University of Washington, Seattle, WA, 98195, USA.
Marvin WhiteleyDepartment of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA.ORCID http://orcid.org/0000-0001-6590-4703
Atsuo AmanoDepartment of Preventive Dentistry, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Huizhi WangDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, 40292, USA.
Edward M MarcotteInstitute for Cellular and Molecular Biology, and Center for Systems and Synthetic Biology, The University of Texas at Austin, Austin, TX, 78712, USA.
Murray HackettCenter for Microbial Proteomics and Chemical Engineering, University of Washington, Seattle, WA, 98195, USA.
Richard J LamontDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, 40292, USA. rich.lamont@louisville.edu.ORCID http://orcid.org/0000-0002-3147-5039
University of Louisville · USUniversity of Washington · USThe University of Osaka · JPThe University of Texas at Austin · USJapan Agency for Medical Research and Development · JP
Funding
MOLECULAR ASPECTS OF ORAL PLAQUE FORMATIONR01DE012505 · NIDCR · UNIVERSITY OF WASHINGTON · PI Richard J Lamont, JAN S POTEMPA · 1998 to 2026
$9.5MProteomics and model organism humanization to decode human geneticsR35GM122480 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI EDWARD M MARCOTTE · 2017 to 2026
$5.4MP GINGIVALIS INTERACTIONS WITH GINGIVAL EPITHELIAL CELLSR01DE011111 · NIDCR · UNIVERSITY OF WASHINGTON · PI HARIBABU BODDULURI, Richard J Lamont · 1995 to 2026
$5.4MProbing Polymicrobial Synergy Using hihg Throughout GenomicsR01DE023193 · NIDCR · UNIVERSITY OF TEXAS AT AUSTIN · PI LAMONT, RICHARD J, WHITELEY, MARVIN · 2013 to 2023
$4.7MNext-Generation Proteomics: Massively Parallel Single-Molecule Protein IdentificaDP1GM106408 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI MARCOTTE, EDWARD M · 2012 to 2016
$3.8MProteomics of Porphyromonas gingivalis interactions with Fusobacterium nucleatumR01DE014372 · NIDCR · UNIVERSITY OF WASHINGTON · PI HACKETT, MURRAY · 2003 to 2014
$3.7MP.gingivalis Interactions with Gingival Epithelial CellsR37DE011111 · NIDCR · UNIVERSITY OF LOUISVILLE · PI LAMONT, RICHARD J · 2009 to 2018
$3.6MProteomics of P. gingivalis interactions with F. nucleatum and S. gordoniiR56DE014372 · NIDCR · UNIVERSITY OF WASHINGTON · PI HACKETT, MURRAY · 2009 to 2015
$1.2MNIDCR NIH HHS R01 DE011111NIDCR NIH HHS R01 DE012505NIDCR NIH HHS R01 DE014372NIDCR NIH HHS R01 DE023193NIDCR NIH HHS R37 DE011111NIDCR NIH HHS R56 DE014372NIGMS NIH HHS DP1 GM106408NIGMS NIH HHS R35 GM122480
Abstract
Many human infections are polymicrobial in origin, and interactions among community inhabitants shape colonization patterns and pathogenic potential
Indexed as
Microbial Interactions4-Aminobenzoic AcidAdhesins, BacterialAnimalsBacterial AdhesionBacteroidaceae InfectionsBiofilmsCoinfectionDisease Models, AnimalDysbiosisFemaleHumansMetabolomicsMiceMice, Inbred BALB Cpara-Aminobenzoates4-Aminobenzoic AcidAdhesins, Bacterialpara-Aminobenzoates
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.