ArticleMolecular psychiatry2018
Genetic contributions to Trail Making Test performance in UK Biobank.
Article in Molecular psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genetic landscape of adult executive function reveals a cell-type-specific developmental origin.Nature communications · 2026Pooled it
- Trial
- Editorial: Mental, sensory, physical and life style parameters related to cognitive decline in aging.Frontiers in aging neuroscience · 2026Article
- Identification of novel protective loci for executive function using the trail making test part B in the Long Life Family Study.bioRxiv : the preprint server for biology · 2025Article
- Association of genetic risk of Alzheimer's disease and cognitive function in two European populations.Scientific reports · 2025Article
- Interactions between ABC gene polymorphisms and processing speed in predicting depression severity.BMC psychiatry · 2025Article
- Assessment of symptoms in myalgic encephalomyelitis/chronic fatigue syndrome: a comparative study of existing scales.Frontiers in neurology · 2025Review
- Dynamics of cognitive variability with age and its genetic underpinning in NIHR BioResource Genes and Cognition cohort participants.Nature medicine · 2024Article
- Effects of home-based manual dexterity training on cognitive function among older adults: a randomized controlled trial.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2023Article
- Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders.Biological psychiatry · 2023Article
- Is there a causal relationship between executive function and liability to mental health and substance use? A Mendelian randomization approach.Royal Society open science · 2022Article
- Direct Clipping of Paraclinoid Aneurysm in Conjunction with Extradural Anterior Clinoidectomy: Technical Nuance and Functional Outcome.Journal of neurological surgery. Part B, Skull base · 2022Article
- Incorporating a Usual Care Comparator into a Study of Meditation and Music Listening for Older Adults with Subjective Cognitive Decline: A Randomized Feasibility Trial.Journal of Alzheimer's disease reports · 2021Article
- Adults With Mild-to-Moderate Congenital Heart Disease Demonstrate Measurable Neurocognitive Deficits.Journal of the American Heart Association · 2020Article
- The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain.PLoS genetics · 2019Article
- Selectively Enhanced Development of Working Memory in Musically Trained Children and Adolescents.Frontiers in integrative neuroscience · 2019Article
- Genetic risk for neurodegenerative disorders, and its overlap with cognitive ability and physical function.PloS one · 2018Article
- Article
- Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
The Trail Making Test (TMT) is a widely used test of executive function and has been thought to be strongly associated with general cognitive function. We examined the genetic architecture of the TMT and its shared genetic aetiology with other tests of cognitive function in 23 821 participants from UK Biobank. The single-nucleotide polymorphism-based heritability estimates for trail-making measures were 7.9% (part A), 22.4% (part B) and 17.6% (part B-part A). Significant genetic correlations were identified between trail-making measures and verbal-numerical reasoning (r
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.