Evidence map›Paper›PMID 28924048›Full record

ArticleThe Journal of biological chemistry2017

A mutant of the

Yijia Xu, Xiangxue Meng, Xue Hou, Jianfang Sun, Xiaohua Kong, Yuqi Sun, Zeyu Liu, Yuanyuan Ma, Ye Niu, Yongbo Song and 3 more

Abstract readComparative Study
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
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  8. Article
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  14. Review
  15. Article
  16. The Pivotal Potentials of ScorpionEvidence-based complementary and alternative medicine : eCAM · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yijia XuFrom the School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016.
Xiangxue MengFrom the School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016.
Xue HouFrom the School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016.
Jianfang Sunthe College of Life and Health Sciences, Northeastern University, Shenyang, Liaoning 110004, and.
Xiaohua KongFrom the School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016.
Yuqi SunFrom the School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016.
Zeyu LiuFrom the School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016.
Yuanyuan MaFrom the School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016.
Ye NiuFrom the School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016.
Yongbo SongFrom the School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016.
Yong Cuithe School of Medical Devices, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, China.
Mingyi ZhaoFrom the School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, zmy_dl@126.com.
Jinghai Zhangthe School of Medical Devices, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, China zhangjinghai@syphu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scorpion toxins can kill other animals by inducing paralysis and arrhythmia, which limits the potential applications of these agents in the clinical management of diseases. Antitumor-analgesic peptide (AGAP), purified from

Indexed as

MutationAmino Acid SubstitutionAnalgesics, Non-NarcoticAnimalsAntineoplastic AgentsArthropod ProteinsCHO CellsCricetulusDose-Response Relationship, DrugFemaleHumansMaleMiceNAV1.4 Voltage-Gated Sodium ChannelNAV1.5 Voltage-Gated Sodium ChannelPeptidesAnalgesics, Non-NarcoticAntineoplastic Agentsantitumor-analgesic peptide, Buthus martensiiArthropod ProteinsNAV1.4 Voltage-Gated Sodium ChannelNAV1.5 Voltage-Gated Sodium ChannelPeptidesRecombinant ProteinsSCN4A protein, humanSCN5A protein, humanScorpion VenomsVoltage-Gated Sodium Channel BlockersAGAPelectrophysiologyhNav1.4hNav1.5painpeptidessodium channeltoxicityTrp38

Identifiers

PMID28924048
PMCPMC5672049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.