Evidence map›Paper›PMID 28924032›Full record

ArticleJournal of bacteriology2017

Staphylococcus aureus Strain Newman D2C Contains Mutations in Major Regulatory Pathways That Cripple Its Pathogenesis.

William E Sause, Richard Copin, Aidan O'Malley, Rita Chan, Brian J Morrow, Peter T Buckley, Jeffrey Fernandez, A Simon Lynch, Bo Shopsin, Victor J Torres

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Machine learning assisted identification of antibiotic-resistantMicrochemical journal : devoted to the application of microtechniques in all branches of science · 2024
    Article
  4. Feline Otitis Externa Caused by Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

William E SauseDepartment of Microbiology, New York University School of Medicine, New York, New York, USA.
Richard CopinDepartment of Microbiology, New York University School of Medicine, New York, New York, USA.
Aidan O'MalleyDepartment of Microbiology, New York University School of Medicine, New York, New York, USA.
Rita ChanDepartment of Microbiology, New York University School of Medicine, New York, New York, USA.
Brian J MorrowJanssen Research and Development, Raritan, New Jersey, USA.
Peter T BuckleyJanssen Research and Development, Spring House, Pennsylvania, USA.
Jeffrey FernandezJanssen Research and Development, Spring House, Pennsylvania, USA.
A Simon LynchJanssen Research and Development, Spring House, Pennsylvania, USA.
Bo ShopsinDepartment of Microbiology, New York University School of Medicine, New York, New York, USA.
Victor J TorresDepartment of Microbiology, New York University School of Medicine, New York, New York, USA victor.torres@nyumc.org.
New York University · USJanssen (United States) · US

Funding

INFECTIOUS DISEASES &BASIC MICROBIOLOGICAL MECHANISMST32AI007180 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WEISER, JEFFREY NEAL · 1985 to 2022
$8.9M
Role of precipitous virulence in invasiveness of community-acquired methicillin-rR01AI103268 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO, TORRES, VICTOR J. · 2013 to 2017
$2.1M
NIAID NIH HHS HHSN272201400019CNIAID NIH HHS R01 AI103268NIAID NIH HHS T32 AI007180
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ProteinsGene Expression Regulation, BacterialGenome, BacterialMutationPolymorphism, Single NucleotideStaphylococcus aureusTranscription FactorsVirulenceWhole Genome SequencingBacterial ProteinsSaeR protein, Staphylococcus aureusTranscription Factorsgenome analysisinfectionNewmanpathogenesispolymorphismStaphylococcustoxinsvirulenceWGS

Identifiers

PMID28924032
PMCPMC5686614
OpenAlexW2754975658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.