Evidence map›Paper›PMID 28924022›Full record

ArticleGut2018

Pan-genomic analyses identify key

Jennifer M Noto, Abha Chopra, John T Loh, Judith Romero-Gallo, M Blanca Piazuelo, Mark Watson, Shay Leary, Amber C Beckett, Keith T Wilson, Timothy L Cover and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Gut, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Microbiology and molecular biology reviews : MMBR · 2026
    Review
  3. Multiple TonB-dependent transport systems inInfection and immunity · 2026
    Article
  4. Article
  5. Infection and immunity · 2025
    Article
  6. Review
  7. Digestive cancers: mechanisms, therapeutics and management.Signal transduction and targeted therapy · 2025
    Review
  8. IRON DEFICIENCY PROMOTESTransactions of the American Clinical and Climatological Association · 2025
    Article
  9. Real-World Situation of Eradication Regimens and Risk Factors forClinical and experimental gastroenterology · 2024
    Article
  10. A Positively SelectedInfection and immunity · 2023
    Article
  11. International journal of molecular sciences · 2022
    Review
  12. Article
  13. Article
  14. Review
  15. Genetics of Host Protection againstInternational journal of molecular sciences · 2021
    Review
  16. Review of current diagnostic methods and advances inWorld journal of gastroenterology · 2019
    Review
  17. Article
  18. Article
  19. CarcinogenicMolecular & cellular proteomics : MCP · 2019
    Article
  20. PeerJ · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Jennifer M NotoDepartment of Medicine, Division of Gastroenterology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Abha ChopraInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Australia.
John T LohDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Judith Romero-GalloDepartment of Medicine, Division of Gastroenterology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
M Blanca PiazueloDepartment of Medicine, Division of Gastroenterology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Mark WatsonInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Australia.
Shay LearyInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Australia.
Amber C BeckettDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Keith T WilsonDepartment of Medicine, Division of Gastroenterology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Timothy L CoverDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Simon MallalInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Australia.
Dawn A IsraelDepartment of Medicine, Division of Gastroenterology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Richard M PeekDepartment of Medicine, Division of Gastroenterology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Vanderbilt University Medical Center · USMurdoch University · AUVA Tennessee Valley Healthcare System · US

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Role of Iron and B-Catenin Activation in Gastric CarcinogenesisP01CA116087 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Kevin L Schey · 2009 to 2026
$27.5M
Project 3 - Molecular Signatures of Gastric Carcinogenesis in the Host Response to H. pyloriP01CA028842 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WILSON, KEITH T. · 1985 to 2019
$15.8M
H.Pylori Relationship to Digestive Diseases and CancerR01CA077955 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2003 to 2026
$9.7M
Structure-function analysis of H. pylori VacAR01AI039657 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TIMOTHY L COVER · 1996 to 2026
$8.3M
Helicobacter Pylori and Gastrointestinal BiologyR01DK058587 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PEEK, RICHARD M. · 2001 to 2024
$7.8M
Type IV Protein Secretion in Helicobacter pyloriR01AI118932 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COVER, TIMOTHY L, OHI, MELANIE DIANE · 2016 to 2025
$6.7M
HPYLORI INDUCED DNA DAMAGE AND IMMUNE DYSREGULATIONR01DK053620 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WILSON, KEITH T. · 1997 to 2014
$3.4M
Targeted chemoprevention of gastric carcinogenesis in high risk populationsR01CA190612 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MORGAN, DOUGLAS, WILSON, KEITH T. · 2014 to 2018
$3.0M
Arginine Availability and Metabolism in the Immune Evasion of H. pyloriI01BX001453 · VA · VETERANS HEALTH ADMINISTRATION · PI WILSON, KEITH T. · 2012 to 2019
–
BLRD VA I01 BX001453NCI NIH HHS P01 CA028842NCI NIH HHS P01 CA116087NCI NIH HHS R01 CA077955NCI NIH HHS R01 CA190612NIAID NIH HHS R01 AI039657NIAID NIH HHS R01 AI118932NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK053620NIDDK NIH HHS R01 DK058587
6 · The paper itself

Abstract

objective

designWhole genome sequencing of genetically related

resultsA total of 180 unique single nucleotide polymorphisms (SNPs) were identified among the collective genomes when compared with a reference

conclusionThese results indicate that specific genetic variation arises within

Indexed as

CarcinogenesisHelicobacter InfectionsHelicobacter pyloriStomach NeoplasmsBacterial ProteinsHumansIn Vitro TechniquesPolymorphism, Single NucleotideBacterial Proteinsgastric cancerHelicobacter pylorihigh saltiron deficiency

Identifiers

PMID28924022
PMCPMC5857411
OpenAlexW2755314437

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.