ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
Reward-Related Ventral Striatum Activity Buffers against the Experience of Depressive Symptoms Associated with Sleep Disturbances.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Too Tired to Think: Within and Between-Person Relations Among Impulsive Traits, Sleep Duration, and Mental Health Outcomes.International journal of mental health and addiction · 2024Article
- Sleep disturbance and social reward processing as characteristics linking minority victimization and suicidal ideation in youth.Frontiers in neuroscience · 2024Article
- Poorer sleep health is associated with altered brain activation during cognitive control processing in healthy adults.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Poor sleep quality is significantly associated with effort but not temporal discounting of monetary rewards.Motivation science · 2022Article
- Associations between childhood family emotional health, fronto-limbic grey matter volume, and saliva 5mC in young adulthood.Clinical epigenetics · 2021Article
- Offensive Behavior, Striatal Glutamate Metabolites, and Limbic-Hypothalamic-Pituitary-Adrenal Responses to Stress in Chronic Anxiety.International journal of molecular sciences · 2020Article
- The subcortical belly of sleep: New possibilities in neuromodulation of basal ganglia?Sleep medicine reviews · 2020Review
- An Integrated Sleep and Reward Processing Model of Major Depressive Disorder.Behavior therapy · 2020Article
- Divergence of an association between depressive symptoms and a dopamine polygenic score in Caucasians and Asians.European archives of psychiatry and clinical neuroscience · 2020Article
- Increased Reward-Related Activation in the Ventral Striatum During Stress Exposure Associated With Positive Affect in the Daily Life of Young Adults With a Family History of Depression. Preliminary Findings.Frontiers in psychiatry · 2020Article
- A genome-wide association study-derived polygenic score for interleukin-1β is associated with hippocampal volume in two samples.Human brain mapping · 2019Article
- Differentiation of Transformed Bipolar Disorder From Unipolar Depression by Resting-State Functional Connectivity Within Reward Circuit.Frontiers in psychology · 2018Article
- Decreased Connection Between Reward Systems and Paralimbic Cortex in Depressive Patients.Frontiers in neuroscience · 2018Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Sleep disturbances represent one risk factor for depression. Reward-related brain function, particularly the activity of the ventral striatum (VS), has been identified as a potential buffer against stress-related depression. We were therefore interested in testing whether reward-related VS activity would moderate the effect of sleep disturbances on depression in a large cohort of young adults. Data were available from 1129 university students (mean age 19.71 ± 1.25 years; 637 women) who completed a reward-related functional MRI task to assay VS activity and provided self-reports of sleep using the Pittsburgh Sleep Quality Index and symptoms of depression using a summation of the General Distress/Depression and Anhedonic Depression subscales of the Mood and Anxiety Symptoms Questionnaire-short form. Analyses revealed that as VS activity increased the association between sleep disturbances and depressive symptoms decreased. The interaction between sleep disturbances and VS activity was robust to the inclusion of sex, age, race/ethnicity, past or present clinical disorder, early and recent life stress, and anxiety symptoms, as well as the interactions between VS activity and early or recent life stress as covariates. We provide initial evidence that high reward-related VS activity may buffer against depressive symptoms associated with poor sleep. Our analyses help advance an emerging literature supporting the importance of individual differences in reward-related brain function as a potential biomarker of relative risk for depression.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.