Evidence map›Paper›PMID 28923972›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Small genome symbiont underlies cuticle hardness in beetles.

Hisashi Anbutsu, Minoru Moriyama, Naruo Nikoh, Takahiro Hosokawa, Ryo Futahashi, Masahiko Tanahashi, Xian-Ying Meng, Takashi Kuriwada, Naoki Mori, Kenshiro Oshima and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 171 citations in OpenAlex.

  1. Article
  2. A bacterial symbiont and a plant virus enhance insect fitness by inducing physical defenses against fungal parasites.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Gene Expression During Scale Development in Pachyrhynchus Weevils.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2026
    Article
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  11. Review
  12. Article
  13. An endosymbiotic origin of the crimson pigment from the lac insect.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Review
  15. Complete genome of the mutualistic symbiont "Microbiology resource announcements · 2025
    Article
  16. Article
  17. Article
  18. Article
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  20. Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 1 country.

Hisashi AnbutsuBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8566, Japan; h-anbutsu@aist.go.jp t-fukatsu@aist.go.jp.
Minoru MoriyamaBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8566, Japan.
Naruo NikohDepartment of Liberal Arts, The Open University of Japan, Chiba 261-8586, Japan.
Takahiro HosokawaBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8566, Japan.
Ryo FutahashiBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8566, Japan.
Masahiko TanahashiBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8566, Japan.
Xian-Ying MengBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8566, Japan.
Takashi KuriwadaNational Agriculture and Food Research Organization, Kyushu Okinawa Agricultural Research Center, Okinawa 901-0336, Japan.
Naoki MoriDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan.
Kenshiro OshimaGraduate School of Frontier Sciences, University of Tokyo, Chiba 277-8561, Japan.
Masahira HattoriGraduate School of Frontier Sciences, University of Tokyo, Chiba 277-8561, Japan.
Manabu FujieDNA Sequencing Section, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan.
Noriyuki SatohMarine Genomics Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan.
Taro MaedaNIBB Core Research Facilities, National Institute for Basic Biology, Okazaki 444-8585, Japan.ORCID 0000-0003-4185-0135
Shuji ShigenobuNIBB Core Research Facilities, National Institute for Basic Biology, Okazaki 444-8585, Japan.
Ryuichi KogaBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8566, Japan.
Takema FukatsuBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8566, Japan; h-anbutsu@aist.go.jp t-fukatsu@aist.go.jp.ORCID 0000-0001-5987-2602
National Institute of Advanced Industrial Science and Technology · JPNational Institute for Basic Biology · JPOkinawa Institute of Science and Technology Graduate University · JPKagoshima University · JPKyoto University · JPKyushu University · JPThe Open University of Japan · JPThe University of Tokyo · JPUniversity of Tsukuba · JPWaseda University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Beetles, representing the majority of the insect species diversity, are characterized by thick and hard cuticle, which plays important roles for their environmental adaptation and underpins their inordinate diversity and prosperity. Here, we report a bacterial endosymbiont extremely specialized for sustaining beetle's cuticle formation. Many weevils are associated with a γ-proteobacterial endosymbiont lineage

Indexed as

Genome, BacterialSymbiosisAnimalsBacteriaBacterial Physiological PhenomenaEvolution, MolecularGene Expression ProfilingHigh-Throughput Nucleotide SequencingHost-Pathogen InteractionsIntegumentary SystemTransaminasesTyrosineWeevilsTransaminasesTyrosinegenomeNardonellasymbionttyrosineweevil

Identifiers

PMID28923972
PMCPMC5635926
OpenAlexW2755607068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.