Evidence map›Paper›PMID 28923933›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Longitudinal identification of clinically distinct neurophenotypes in young children with fragile X syndrome.

Jennifer L Bruno, David Romano, Paul Mazaika, Amy A Lightbody, Heather Cody Hazlett, Joseph Piven, Allan L Reiss

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Developmental studies in fragile X syndrome.Journal of neurodevelopmental disorders · 2020
    Review
  10. Review
  11. Review
  12. Artificial Intelligence in Cardiovascular Medicine.Current treatment options in cardiovascular medicine · 2019
    Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jennifer L BrunoCenter for Interdisciplinary Brain Sciences Research, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305-5795; jenbruno@stanford.edu dromano@stanford.edu.
David RomanoCenter for Interdisciplinary Brain Sciences Research, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305-5795; jenbruno@stanford.edu dromano@stanford.edu.
Paul MazaikaCenter for Interdisciplinary Brain Sciences Research, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305-5795.
Amy A LightbodyCenter for Interdisciplinary Brain Sciences Research, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305-5795.
Heather Cody HazlettCarolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-2267.
Joseph PivenCarolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-2267.
Allan L ReissCenter for Interdisciplinary Brain Sciences Research, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305-5795.
Stanford University · USUniversity of North Carolina at Chapel Hill · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
Longitudinal MRI Study of Brain Development in Fragile XR01MH064708 · NIMH · STANFORD UNIVERSITY · PI PIVEN, JOSEPH, REISS, ALLAN L · 2002 to 2016
$8.1M
TRAINING FOR CHILD PSYCHIATRY AND CHILD DEVELOPMENTT32MH019908 · NIMH · STANFORD UNIVERSITY · PI IAN H GOTLIB, DAVID S HONG · 1993 to 2026
$6.3M
NIEHS NIH HHS P30 ES010126NIMH NIH HHS R01 MH064708NIMH NIH HHS T32 MH019908
6 · The paper itself

Abstract

Fragile X syndrome (FXS), due to mutations of the

Indexed as

Child DevelopmentCognitionBrainChild, PreschoolFemaleFragile X SyndromeHumansImage Processing, Computer-AssistedLongitudinal StudiesMagnetic Resonance ImagingMaleNeuropsychological TestsPhenotypeautism spectrum behaviorfragile X syndromelongitudinal developmentMRImultivariate pattern classification

Identifiers

PMID28923933
PMCPMC5635864
OpenAlexW2755812327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.