Evidence map›Paper›PMID 28923929›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C

Rashmi Voleti, Diana R Tomchick, Thomas C Südhof, Josep Rizo

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
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  7. Complexin has a dual synaptic function as checkpoint protein in vesicle priming and as a promoter of vesicle fusion.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Mechanism and cellular function of direct membrane binding by the ESCRT and ERES-associated CaProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
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  12. Review
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  15. Article
  16. Article
  17. Article
  18. 5-IPNature metabolism · 2021
    Article
  19. Article
  20. Function of Drosophila Synaptotagmins in membrane trafficking at synapses.Cellular and molecular life sciences : CMLS · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rashmi VoletiDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Diana R TomchickDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Thomas C SüdhofDepartment of Molecular and Cellular Physiology, Stanford University Medical School, Stanford, CA 94305; tcs1@stanford.edu jose.rizo-rey@UTSouthwestern.edu.
Josep RizoDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390; tcs1@stanford.edu jose.rizo-rey@UTSouthwestern.edu.
The University of Texas Southwestern Medical Center · USHoward Hughes Medical Institute · US

Funding

Mechanisms of neurotransmitter release and its regulationR35NS097333 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 2017 to 2024
$7.0M
STRUCTURE/FUNCTION OF SYNTAXIN 1R01NS037200 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 1998 to 2016
$6.5M
SYNAPTOTAGMIN AND C2 DOMAINS--STRUCTURE AND FUNCTIONR01NS040944 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 2001 to 2016
$6.4M
Acquisition of upgrades for 800 MHz NMR consoleS10OD018027 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 2014 to 2014
$376k
600MHz Varian VNMRS Console UpgradeS10RR026461 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI ROSEN, MICHAEL K · 2010 to 2010
$254k
Howard Hughes Medical InstituteNCRR NIH HHS S10 RR026461NIH HHS S10 OD018027NINDS NIH HHS R01 NS037200NINDS NIH HHS R01 NS040944NINDS NIH HHS R35 NS097333
6 · The paper itself

Abstract

Synaptotagmins (Syts) act as Ca

Indexed as

AnimalsCalciumCell MembraneCrystallography, X-RayLiposomesNeurotransmitter AgentsProtein BindingProtein DomainsRatsSynaptic TransmissionSynaptotagmin ISynaptotagminsCalciumLiposomesNeurotransmitter AgentsSynaptotagmin ISynaptotagminsSyt1 protein, ratSyt7 protein, ratmembrane bindingneurotransmitter releasesynaptotagmin-1synaptotagmin-7X-ray crystallography

Identifiers

PMID28923929
PMCPMC5635908
OpenAlexW2756163062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.