Evidence map›Paper›PMID 28923894›Full record

ArticleInfection and immunity2017

H-IPSE Is a Pathogen-Secreted Host Nucleus-Infiltrating Protein (Infiltrin) Expressed Exclusively by the Schistosoma haematobium Egg Stage.

Luke F Pennington, Abdulaziz Alouffi, Evaristus C Mbanefo, Debalina Ray, David M Heery, Theodore S Jardetzky, Michael H Hsieh, Franco H Falcone

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. O-GlcNAcylation: Crosstalk between Hemostasis, Inflammation, and Cancer.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Schistosome immunomodulators.PLoS pathogens · 2021
    Review
  6. Article
  7. DoesCells · 2021
    Review
  8. Review
  9. Pathogens (Basel, Switzerland) · 2021
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Luke F Pennington *Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-7947-8714
Abdulaziz Alouffi *School of Pharmacy, Division of Molecular Therapeutics and Formulation, University of Nottingham, Nottingham, United Kingdom.
Evaristus C MbanefoBiomedical Research Institute, Rockville, Maryland, USA.
Debalina RayDepartment of Pathology, University of California, San Francisco, California, USA.
David M HeerySchool of Pharmacy, Division of Biomolecular Science and Medicinal Chemistry, University of Nottingham, Nottingham, United Kingdom.
Theodore S JardetzkyStanford University School of Medicine, Stanford, California, USA.
Michael H HsiehBiomedical Research Institute, Rockville, Maryland, USA.
Franco H FalconeSchool of Pharmacy, Division of Molecular Therapeutics and Formulation, University of Nottingham, Nottingham, United Kingdom franco.falcone@nottingham.ac.uk.ORCID 0000-0002-1732-9932
University of Nottingham · GBStanford University · USBiomedical Research Institute · USGeorge Washington University · USUniversity of California, San Francisco · US

Funding

MOLECULAR &CELLULAR IMMUNOBIOLOGYT32AI007290 · NIAID · STANFORD UNIVERSITY · PI Sean Curtis Bendall, Olivia M Martinez · 1985 to 2026
$27.0M
Therapeutic Exploitation of IPSE, a Urogenital Parasite-Derived Host Modulatory Protein, for Bladder Hypersensitivity SyndromesR01DK113504 · NIDDK · CHILDREN'S RESEARCH INSTITUTE · PI HSIEH, MICHAEL HARRISON · 2017 to 2021
$2.4M
Defining the Immunomodulatory Niche of Schistosoma haematobium IPSER56AI119168 · NIAID · BIOMEDICAL RESEARCH INSTITUTE · PI HSIEH, MICHAEL HARRISON · 2015 to 2015
$471k
NIAID NIH HHS R56 AI119168NIDDK NIH HHS R01 DK113504
6 · The paper itself

Abstract

Urogenital schistosomiasis, caused by the parasitic trematode

Indexed as

AnimalsCell Line, TumorCell NucleusCloning, MolecularDNA-Binding ProteinsEgg ProteinsHelminth ProteinsHumansImmunomodulationInflammationOvumRecombinant ProteinsSchistosoma haematobiumSchistosomiasis haematobiaUrinary BladderDNA-Binding ProteinsEgg ProteinsHelminth ProteinsIPSE protein, Schistosoma mansoniRecombinant Proteinsnuclear localization signalSchistosoma haematobiumschistosomiasis

Identifiers

PMID28923894
PMCPMC5695104
OpenAlexW2754942940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.