Evidence map›Paper›PMID 28923880›Full record

Trial reportClinical science (London, England : 1979)2017

Impact of liver fat on the differential partitioning of hepatic triacylglycerol into VLDL subclasses on high and low sugar diets.

A Margot Umpleby, Fariba Shojaee-Moradie, Barbara Fielding, Xuefei Li, Andrea Marino, Najlaa Alsini, Cheryl Isherwood, Nicola Jackson, Aryati Ahmad, Michael Stolinski and 10 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical science (London, England : 1979), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 4 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Tolerable upper intake level for dietary sugars.EFSA journal. European Food Safety Authority · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 1 institution in 1 country.

A Margot UmplebyFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K.
Fariba Shojaee-MoradieFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K.
Barbara FieldingFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K.
Xuefei LiFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K.
Andrea MarinoFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K.
Najlaa AlsiniFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K.
Cheryl IsherwoodFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K.
Nicola JacksonFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K.
Aryati AhmadFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K.
Michael StolinskiFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K.
Julie A LovegroveHugh Sinclair Unit of Human Nutrition and Institute for Cardiovascular and Metabolic Research, University of Reading, Reading, U.K.
Sigurd JohnsenFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K.
A S Jeewaka R MendisFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K.
John WrightFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K.
Malgorzata E WilinskaDiabetes Modelling Group, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K.
Roman HovorkaDiabetes Modelling Group, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K.
Jimmy D BellMetabolic and Molecular Imaging Group, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London, U.K.
E Louise ThomasMetabolic and Molecular Imaging Group, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London, U.K.
Gary S FrostNutrition and Dietetic Research Group, Section of Investigative Medicine, Division of Diabetes, Endocrinology and Metabolism, Imperial College London, U.K.
Bruce A GriffinFaculty of Health and Medical Sciences, University of Surrey, Guildford, U.K. b.griffin@surrey.ac.uk.
University of Surrey · GB

Funding

Biotechnology and Biological Sciences Research Council BB/G008272/1Biotechnology and Biological Sciences Research Council BB/G009899/1Medical Research Council MC_U120061305
6 · The paper itself

Abstract

Dietary sugars are linked to the development of non-alcoholic fatty liver disease (NAFLD) and dyslipidaemia, but it is unknown if NAFLD itself influences the effects of sugars on plasma lipoproteins. To study this further, men with NAFLD (

Indexed as

AdultAgedCross-Over StudiesDietary CarbohydratesEnzyme-Linked Immunosorbent AssayFastingFatsHumansLipidsLipoproteins, VLDLLiverMagnetic Resonance ImagingMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseOutcome Assessment, Health CareDietary CarbohydratesFatsLipidsLipoproteins, VLDLTriglyceridesnon alcoholic fatty liver diseaseplasma lipoproteinsSugartriglycerides

Identifiers

PMID28923880
PMCPMC6365592
OpenAlexW2756166739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.