Evidence map›Paper›PMID 28923788›Full record

Trial reportJournal of medical Internet research2017

Video Game Intervention for Sexual Risk Reduction in Minority Adolescents: Randomized Controlled Trial.

Lynn E Fiellin, Kimberly D Hieftje, Tyra M Pendergrass, Tassos C Kyriakides, Lindsay R Duncan, James D Dziura, Benjamin G Sawyer, Linda Mayes, Cindy A Crusto, Brian Wc Forsyth and 1 more

3 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medical Internet research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 39 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 8 pooled it
16.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01666496 nacompletednot on this map

An Interactive Video Game for HIV Prevention in Early Adolescents

TypeinterventionalSponsorYale UniversityRan2013 to 2016Enrolled333ConditionsHIV, Risk ReductionArmsExperimental Video Game, Off the Shelf Video Game
NCT06171633 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Ending Sexual Harassment - Teaching Of Principal Investigators

TypeinterventionalSponsorStanford UniversityRan2024 to 2027Enrolled2,160ConditionsSexual HarassmentArmsE-STOP online educational program (treatment condition), E-STOP online educational program (control condition)
NCT06307002 nacompletednot on this mapstarted 2024, after this paper: background citation

Evaluating the Impact of a Contraception Education Game: What's My Method? on Contraceptive Self-efficacy and Clinical Outcomes in Barbados

TypeinterventionalSponsorQuinnipiac UniversityRan2024 to 2024Enrolled70ConditionsContraception BehaviorArmsPlaying a contraception education videogame
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 8 syntheses or guidelines pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Effectiveness of digital interventions to reduce school-age adolescent sexual risks: A systematic review.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2025
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Trial
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  11. A Serious Video Game Targeting HIV Testing and Counseling: A Randomized Controlled Trial.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2024
    Trial
  12. Trial
  13. Article
  14. Review
  15. Article
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  18. Let's Talk About Condoms: Social Engagement in a Sexual Health Intervention Targeting Young Adults in Denmark.International journal of sexual health : official journal of the World Association for Sexual Health · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 3 countries.

Lynn E Fiellinplay2PREVENT Lab, Yale School of Medicine, Yale University, New Haven, CT, United States.ORCID 0000-0003-0160-6613
Kimberly D Hieftjeplay2PREVENT Lab, Yale School of Medicine, Yale University, New Haven, CT, United States.ORCID 0000-0001-9276-7767
Tyra M Pendergrassplay2PREVENT Lab, Yale School of Medicine, Yale University, New Haven, CT, United States.ORCID 0000-0002-2750-2321
Tassos C KyriakidesYale School of Public Health, Yale University, New Haven, CT, United States.ORCID 0000-0001-8913-108X
Lindsay R Duncanplay2PREVENT Lab, Yale School of Medicine, Yale University, New Haven, CT, United States.ORCID 0000-0002-2861-3349
James D DziuraYale School of Public Health, Yale University, New Haven, CT, United States.ORCID 0000-0001-8953-6183
Benjamin G Sawyerplay2PREVENT Lab, Yale School of Medicine, Yale University, New Haven, CT, United States.ORCID 0000-0003-2750-0542
Linda MayesYale Child Study Center, New Haven, CT, United States.ORCID 0000-0002-9590-7128
Cindy A CrustoCenter for Interdisciplinary Research on AIDS, Yale School of Public Health, Yale University, New Haven, CT, United States.ORCID 0000-0003-3300-3040
Brian Wc ForsythCenter for Interdisciplinary Research on AIDS, Yale School of Public Health, Yale University, New Haven, CT, United States.ORCID 0000-0001-5562-2032
David A Fiellinplay2PREVENT Lab, Yale School of Medicine, Yale University, New Haven, CT, United States.ORCID 0000-0002-4006-010X
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Treatment Development & Evaluation CoreP30DA029926 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2011 to 2026
$21.5M
An Interactive Video Game for HIV Prevention in At-Risk AdolescentsR01HD062080 · NICHD · YALE UNIVERSITY · PI FIELLIN, LYNN ELIZABETH · 2009 to 2013
$3.8M
NCATS NIH HHS UL1 TR001863NICHD NIH HHS R01 HD062080NIDA NIH HHS P30 DA029926
6 · The paper itself

Abstract

backgroundHuman immunodeficiency virus (HIV) disproportionately impacts minority youth. Interventions to decrease HIV sexual risk are needed.

objectiveWe hypothesized that an engaging theory-based digital health intervention in the form of an interactive video game would improve sexual health outcomes in adolescents.

methodsParticipants aged 11 to 14 years from 12 community afterschool, school, and summer programs were randomized 1:1 to play up to 16 hours of an experimental video game or control video games over 6 weeks. Assessments were conducted at 6 weeks and at 3, 6, and 12 months. Primary outcome was delay of initiation of vaginal/anal intercourse. Secondary outcomes included sexual health attitudes, knowledge, and intentions. We examined outcomes by gender and age.

resultsA total of 333 participants were randomized to play the intervention (n=166) or control games (n=167): 295 (88.6%) were racial/ethnic minorities, 177 (53.2%) were boys, and the mean age was 12.9 (1.1) years. At 12 months, for the 258 (84.6%) participants with available data, 94.6% (122/129) in the intervention group versus 95.4% (123/129) in the control group delayed initiation of intercourse (relative risk=0.99, 95% CI 0.94-1.05, P=.77). Over 12 months, the intervention group demonstrated improved sexual health attitudes overall compared to the control group (least squares means [LS means] difference 0.37, 95% CI 0.01-0.72, P=.04). This improvement was observed in boys (LS means difference 0.67, P=.008), but not girls (LS means difference 0.06, P=.81), and in younger (LS means difference 0.71, P=.005), but not older participants (LS means difference 0.03, P=.92). The intervention group also demonstrated increased sexual health knowledge overall (LS means difference 1.13, 95% CI 0.64-1.61, P<.001), in girls (LS means difference 1.16, P=.001), boys (LS means difference 1.10, P=.001), younger (LS means difference 1.18, P=.001), and older (LS means difference=1.08, P=.002) participants. There were no differences in intentions to delay the initiation of intercourse between the two groups (LS means difference 0.10, P=.56).

conclusionsAn interactive video game intervention improves sexual health attitudes and knowledge in minority adolescents for at least 12 months.

trial registrationClinicaltrials.gov NCT01666496; https://clinicaltrials.gov/ct2/show/NCT01666496 (Archived by WebCite at http://www.webcitation.org/6syumc9C0).

Indexed as

AdolescentChildFemaleHumansMaleMinority GroupsRisk Reduction BehaviorSexual BehaviorVideo Gamesadolescenthuman immunodeficiency virusinterventionprimary preventionrandomized controlled trialrisk reductionvideogame

Identifiers

PMID28923788
PMCPMC5625130
OpenAlexW2754671727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.