ArticleThe Journal of surgical research2017
The independent effect of cancer on outcomes: a potential limitation of surgical risk prediction.
Article in The Journal of surgical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Psychosocial Interventions for Patients Undergoing Gastrointestinal Cancer Surgery: A Systematic Review.Annals of surgical oncology · 2026Pooled it
- Screening and predictive analysis of common regulatory genes in diabetes and rectal cancer: transcriptional and drug modulation mechanisms.European journal of medical research · 2025Article
- Are patients with active cancer at increased risk of revision surgery after total joint arthroplasty? A propensity-matched study.Archives of orthopaedic and trauma surgery · 2025Article
- Oncology and Acute Care Surgery: Examining Outcomes in Cancer Patients Requiring Emergent Laparotomy.The Journal of surgical research · 2025Article
- The effect of comorbidity on 28-day perioperative mortality rate among non-cardiac surgical patients in Northwest Ethiopia: a prospective cohort study using propensity score matching.BMC public health · 2024Article
- Marijuana's Impact On Implant-based Breast Reconstruction: A Retrospective Cohort Study.Plastic and reconstructive surgery. Global open · 2024Article
- The Predictive Value of a Modified Frailty Index on Perioperative Morbidity and Mortality Following Otologic Surgery.Otology & neurotology open · 2023Article
- Surgical Treatment of Distal Cholangiocarcinoma.Current oncology (Toronto, Ont.) · 2022Review
- Effect of glycated hemoglobin A1c on the survival of patients with oral squamous cell carcinoma: A multi-institutional database cohort study.Frontiers in oncology · 2022Article
- Development of an Enhanced Recovery Program in Pediatric, Adolescent, and Young Adult Surgical Oncology Patients.Children (Basel, Switzerland) · 2021Article
- On All Accounts: Cost-Effectiveness Analysis of Limited Preoperative Optimization Efforts Before Colon Cancer Surgery.Diseases of the colon and rectum · 2021Article
- Postoperative Outcomes Following Elective Surgery in India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
- The Impact of Comorbid Diabetes on Short-Term Postoperative Outcomes in Stage I/II Colon Cancer Patients Undergoing Open Colectomy.BioMed research international · 2020Article
- Article
- Clinical Factors Associated with Longer Hospital Stay Following Ovarian Cancer Surgery.Healthcare (Basel, Switzerland) · 2019Article
- Psychosocial Risks are Independently Associated with Cancer Surgery Outcomes in Medically Comorbid Patients.Annals of surgical oncology · 2019Observational
- Article
- Explainable machine learning/artificial intelligence model for estimating postoperative survival in renal cell carcinoma brain metastasis patients.Neuro-oncology advancesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundCancer patients are often thought to have worse surgical outcomes. There is a growing view that risk models do not adequately predict these outcomes. This study aims to compare the use of common risk models for benign versus malignant gastrointestinal disease. MATERIALS AND
methodsThe National Surgical Quality Improvement Program (NSQIP) 2005-2015 participant use files were queried for patients undergoing elective surgery for benign and malignant diseases with a primary procedure code for major colon, pancreas, or stomach resection. Multivariable logistic regression was performed to identify independent predictors of mortality and morbidity.
resultsWe identified 264,401 cases (111,563 malignant). The gastrointestinal cancer population was disproportionately male, older than 65, nonwhite, and less functionally independent. Comorbidities more common in the cancer population included diabetes, hypertension, dyspnea, and chronic obstructive pulmonary disease. Cancer patients had a longer length of stay (+0.9 days), higher mortality rate (1.7% versus 1.1%), and higher complication rate (27.4% versus 23.2%). NSQIP prediction models for complications in cancer versus noncancer patients underperformed for predicting mortality (P < 0.001). Multivariable regression demonstrated that a diagnosis of cancer requiring surgery independently conferred an 18% increased odds of death, a 9% increased odds of a complication, and an 8% increased odds of multiple complications compared to patients with benign disease.
conclusionsNSQIP prediction models less effectively evaluate the risk of death in cancer patients as compared to patients with benign disease. A diagnosis of cancer is independently associated with an increased risk of surgical complications. Incorporating cancer diagnosis into surgical risk models may better inform patient and surgeon expectations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.