Evidence map›Paper›PMID 28923492›Full record

Trial reportContemporary clinical trials2017

Rationale and design of the Atrial Fibrillation health Literacy Information Technology Trial: (AF-LITT).

Emily N Guhl, Courtney L Schlusser, Lori E Henault, Timothy W Bickmore, Everlyne Kimani, Michael K Paasche-Orlow, Jared W Magnani

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contemporary clinical trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03093558 (Pilot Atrial Fibrillation Information Technology Trial), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03093558 nacompletednot on this map

Pilot Atrial Fibrillation Information Technology Trial

TypeinterventionalSponsorUniversity of PittsburghRan2017 to 2018Enrolled120ConditionsAtrial FibrillationArmsECA/Kardia
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Emily N GuhlDepartment of Medicine, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, United States.
Courtney L SchlusserDivision of Cardiology, Department of Medicine, UPMC Heart and Vascular Institute, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, United States.
Lori E HenaultSection of General Internal Medicine, Department of Medicine, Boston University School of Medicine, 801 Massachusetts Avenue, Boston, MA 02118, United States.
Timothy W BickmoreCollege of Computer and Information Science, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, United States.
Everlyne KimaniCollege of Computer and Information Science, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, United States.
Michael K Paasche-OrlowSection of General Internal Medicine, Department of Medicine, Boston University School of Medicine, 801 Massachusetts Avenue, Boston, MA 02118, United States.
Jared W MagnaniDivision of Cardiology, Department of Medicine, UPMC Heart and Vascular Institute, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, United States. Electronic address: magnanij@pitt.edu.
Boston University · USNortheastern University · USUniversity of Pittsburgh · USUniversity of Pittsburgh Medical Center · US

Funding

Doris Duke Charitable Foundation 2015084
6 · The paper itself

Abstract

backgroundAtrial Fibrillation (AF) is a common cardiac arrhythmia that is challenging for patients and adversely impacts health-related quality of life (HRQoL). Long-term management of AF requires that patients adhere to complex therapies, understand difficult terminology, navigate subspecialty care, and have continued symptom monitoring with the goal of preventing adverse outcomes. Continued interventions to ameliorate the patient experience of AF are essential.

designThe Atrial Fibrillation health Literacy Information Technology Trial (AF-LITT; NCT03093558) is an investigator-initiated, 2-arm randomized clinical trial (RCT). This RCT is a pilot in order to implement a novel, smartphone-based intervention to address the patient experience of AF. This pilot RCT will compare a combination of the Embodied Conversational Agent (ECA) and the Alive Cor Kardia Mobile heart rhythm monitor to the current standard of care. The study will enroll 180 adults with non-valvular AF who are receiving anticoagulation for stroke prevention and randomize them to receive a 30-day intervention (smartphone-based ECA/Kardia) or standard of care, which will include a symptom and adherence journal. The primary end-points are improvement in HRQoL and self-reported adherence to anticoagulation. The secondary end-points are the acceptability of the intervention to participants, its use by participants, and acceptability to referring physicians.

conclusionsThe AF-LITT pilot aims to evaluate the efficacy of the ECA/Kardia to improve HRQoL and anticoagulant adherence, and to guide its implementation in a larger, multicenter clinical trial. The intervention has potential to improve HRQoL, adherence, and health care utilization in individuals with chronic AF.

Indexed as

Drug MonitoringSmartphoneAgedAged, 80 and overAnticoagulantsAtrial FibrillationFemaleHealth LiteracyHumansMaleMiddle AgedMonitoring, AmbulatoryPatient SatisfactionPilot ProjectsQuality of LifeResearch DesignAnticoagulantsAdherenceAtrial fibrillationHealth-related quality of lifeRandomized clinical trialRelational agents

Identifiers

PMID28923492
PMCPMC5641265
OpenAlexW2755391402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.