ArticleJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2018
Blood flow regulation and oxidative stress during submaximal cycling exercise in patients with cystic fibrosis.
Article in Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Circulating biomarkers of antioxidant status and oxidative stress in people with cystic fibrosis: A systematic review and meta-analysis.Redox biology · 2020Pooled it
- Sildenafil improves vascular endothelial function in patients with cystic fibrosis.American journal of physiology. Heart and circulatory physiology · 2018Trial
- Prevalence, risk factors and outcomes of cardiac disease in cystic fibrosis: a multinational retrospective cohort study.The European respiratory journal · 2023Article
- Skeletal muscle contributions to reduced fitness in cystic fibrosis youth.Frontiers in pediatrics · 2023Article
- The Interplay between Oxidative Stress, Exercise, and Pain in Health and Disease: Potential Role of Autonomic Regulation and Epigenetic Mechanisms.Antioxidants (Basel, Switzerland) · 2020Review
- Exercise Physiology Across the Lifespan in Cystic Fibrosis.Frontiers in physiology · 2019Review
- Endothelial Dysfunction in Cystic Fibrosis: Role of Oxidative Stress.Oxidative medicine and cellular longevity · 2019Article
- Cystic Fibrosis Transmembrane Conductance Regulator Genotype, Not Circulating Catecholamines, Influences Cardiovascular Function in Patients with Cystic Fibrosis.Clinical medicine insights. Circulatory, respiratory and pulmonary medicine · 2019Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundThe impact of blood flow regulation and oxidative stress during exercise in cystic fibrosis (CF) has yet to be investigated.
methodsA maximal graded exercise test was conducted to determine exercise capacity (VO
resultsThe cumulative AUC for retrograde velocity was lower in patients versus controls (1770±554 vs. 3440±522cm, P=0.038). In addition, an exaggerated oxidative stress response during exercise occurred in patients only (P=0.004).
conclusionThese data suggest that patients with mild CF exhibit impaired blood flow regulation and an exaggerated oxidative stress response to submaximal exercise.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.