Evidence map›Paper›PMID 28923180›Full record

ReviewMaturitas2017

Menopause in Latin America: Symptoms, attitudes, treatments and future directions in Costa Rica.

T D Locklear, B J Doyle, A L Perez, S M Wicks, G B Mahady

Open access · greenAbstract readReview
In one paragraph

Review in Maturitas, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Brazilian Guideline on Menopausal Cardiovascular Health - 2024.Arquivos brasileiros de cardiologia · 2024
    Guideline
  2. Article
  3. Article
  4. Brazilian Guideline on Menopausal Cardiovascular Health - 2024.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

T D LocklearDuke Clinical Research Institute, 2400 Pratt St. North Pavilion, Duke University Medical Center, Durham, NC 27710, USA.
B J DoyleDepartments of Biology and Biochemistry, Alma College, Alma, MI, USA.
A L PerezCentro de Investigaciones en Productos Naturales (CIPRONA), Natural Products Research Center, University of Costa Rica, San Jose, Costa Rica.
S M WicksRush University Medical Center, Department of Cellular and Molecular Medicine, Chicago, IL, USA.
G B MahadyDepartment of Pharmacy Practice, WHO Collaborating Centre for Traditional Medicine, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA. Electronic address: mahady@uic.edu.
Alma College · USDuke Medical Center · USRush University Medical Center · USUniversidad de Costa Rica · CRUniversity of Illinois Chicago · US

Funding

Botanicals from Central America for MenopauseR21AT002381 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MAHADY, GAIL B · 2004 to 2005
$362k
NCCIH NIH HHS R21 AT002381
6 · The paper itself

Abstract

Similar to their US counterparts, Costa Rican women enter menopause at ∼50 years of age, have similar symptoms, including hot flashes and night sweats, as well as an overall negative attitude toward the menopausal transition. One study of rural women in Monteverde reported that women knew little about the menopausal transition, as the subject was not discussed. Similar to other Latin American women, the use of hormone therapy by Costa Rican women is low and instead they use alternative therapies, including massage, dietary changes and herbal medicines. A wide variety of herbal therapies are used, and some of these herbs have estrogenic activities in vitro. However, clinical data on the safety and efficacy of any of these treatments is lacking. Recently, a disturbing increase in the incidence of human papilloma virus infections in menopausal women has been reported, due in part to more sexual freedom after menopause. Fortunately, the strain of HPV infecting these women is not associated with cervical cancer. Overall, there is a significant lack of scientific and medical research on menopausal women in Costa Rica. Considering the aging population, the high use of herbal medicines by menopausal women and the lack of clinical studies on these treatments, future research should focus on gaining a better understanding of menopause in this population. Furthermore, new educational programs for these women and the health professionals who serve them are necessary, as well as investigations of the safety and efficacy of the herbal supplements women use to manage their menopausal symptoms.

Indexed as

MenopauseAnimalsAttitudeCosta RicaFemaleHumansPapillomavirus InfectionsUterine Cervical NeoplasmsEstrogenEthnically diverseHerbalHPVMenopause

Identifiers

PMID28923180
PMCPMC5616184
OpenAlexW2740821279

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.