ReviewArthritis research & therapy2017
Usefulness of lung ultrasound B-lines in connective tissue disease-associated interstitial lung disease: a literature review.
Review in Arthritis research & therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05041868 (Physical Rehabilitation in Women With Scleroderma), which is not on this map. Cited by 75 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Physical Rehabilitation in Women With Scleroderma: Effects on Pulmonary Function, Lung Ultrasound, Muscle Function, Hand Functional, Functional Capacity, and Quality of Life
Who cites it
75 citing papers in PubMed, 1 synthesis or guideline pooled it, 160 citations in OpenAlex.
- A simplified lung ultrasound for the diagnosis of interstitial lung disease in connective tissue disease: a meta-analysis.Arthritis research & therapy · 2019Pooled it
- Systemic Autoimmune Rheumatic Disease-Associated Interstitial Lung Disease: A Pulmonary Perspective on Recent Guidelines.Advances in therapy · 2026Review
- Ultrasonographic and Thermographic Evaluation in Brachycephalic Dogs Before and After Physical Exercise in the Brazilian Northeast Semi-Arid Region.Veterinary sciences · 2026Article
- Observational
- Current use and practices of lung ultrasound in geriatric care: insights from a national survey.Aging clinical and experimental research · 2026Article
- Lung ultrasound B-line quantification in CTD-ILD: a cross-sectional single-center observational study.Scientific reports · 2026Observational
- Advances in diagnosis of lung fibrosis: focus on present and future approaches.Frontiers in medicine · 2026Review
- Correlation analysis between quantitative lung ultrasound parameters and pulmonary function in idiopathic pulmonary fibrosis: an observational study.Frontiers in medicine · 2026Article
- Clinical features, diagnosis, and treatment of primary Sjögren's disease with interstitial lung disease: A narrative review.Frontiers in immunology · 2026Review
- Thoracic Ultrasound in Assessment of the Pleura in Connective Tissue Disease.Archives of rheumatology · 2025Article
- Comment on Vicente-Rabaneda et al. A Proposal for a New Lung Ultrasound Score in Rheumatoid Arthritis: The Reliability of Lung Ultrasound for Rheumatoid Arthritis-Associated Interstitial Lung Disease Diagnosis.Journal of clinical medicine · 2025Article
- Evaluation of the coalescent lung ultrasound score in rheumatoid arthritis-associated interstitial lung disease.Clinical rheumatology · 2025Article
- The diagnostic utility of lung ultrasound in the assessment of interstitial lung disease associated with rheumatoid arthritis.Arthritis research & therapy · 2025Article
- Thoracic Ultrasound for Acute Dyspnea in Interstitial Lung Disease.Journal of clinical medicine · 2025Article
- Lung Ultrasound After COVID-19: A Pivotal Moment for Clinical Integration-Navigating Challenges and Seizing Opportunities.Healthcare (Basel, Switzerland) · 2025Review
- Thoracic ultrasound in interstitial lung disease.Breathe (Sheffield, England) · 2025Article
- Transthoracic Lung Ultrasound in Systemic Sclerosis-Associated Interstitial Lung Disease: Capacity to Differentiate Chest Computed-Tomographic Characteristic Patterns.Diagnostics (Basel, Switzerland) · 2025Article
- Lung ultrasound for assessing disease progression in UIP and NSIP: a comparative study with HRCT and PFT/DLCO.BMC pulmonary medicine · 2025Article
- Convolutional automatic identification of B-lines and interstitial syndrome in lung ultrasound images using pre-trained neural networks with feature fusion.Frontiers in digital health · 2025Article
- Integrative assessment of congestion in heart failure using ultrasound imaging.Internal and emergency medicine · 2025Review
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interstitial lung disease (ILD) is a major pulmonary manifestation of connective tissue disease (CTD), leading to significant morbidity and mortality. Chest high-resolution computed tomography (HRCT) is presently considered the diagnostic gold standard for pulmonary fibrosis diagnosis and quantification in the clinical arena. However, not negligible doses of ionizing radiation limit the use of HRCT, especially for serial follow-up in younger female patients. In the past decade, lung ultrasound (LUS) has been proposed to assess ILD by detecting and quantifying sonographic B-lines. Previous studies demonstrate that B-lines have a good diagnostic accuracy, especially high sensitivity, and correlate well with HRCT findings, suggesting LUS as a novel, non-invasive, and non-ionizing imaging method to be used in patients with CTD-ILD. Although preliminary data are promising, challenges and controversies still remain. For example, the mechanisms of B-line generation are not fully understood; the diagnostic accuracy and performance characteristics of LUS partially depend on the scanning scheme and scoring system used; and up-to-date B-lines cannot discriminate the early cellular inflammation from the chronic fibrotic phase in CTD-ILD. Therefore it is important for clinicians to understand the strengths and limitations of LUS in CTD-ILD patients, to maximize its value.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.