Evidence map›Paper›PMID 28923073›Full record

ArticleWorld journal of surgical oncology2017

Foxp3 is correlated with VEGF-C expression and lymphangiogenesis in cervical cancer.

Jiabu Tang, Zheng Yang, Zhuo Wang, Zhen Li, Hongmei Li, Jinbao Yin, Min Deng, Wei Zhu, Chao Zeng

Open access · goldAbstract read
In one paragraph

Article in World journal of surgical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Observational
  20. Role of regulatory T cells and CD8Oncology letters · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jiabu TangDepartment of Pathology, Guangdong Medical University, 1 Xincheng Road, Dongguan, 523808, China.
Zheng YangDepartment of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Zhongshan 2nd Road 74, Guangzhou, 510080, China.
Zhuo WangDepartment of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Zhongshan 2nd Road 74, Guangzhou, 510080, China.
Zhen LiDepartment of Pathology, Guangdong Medical University, 1 Xincheng Road, Dongguan, 523808, China.
Hongmei LiDepartment of Pathology, Guangdong Medical University, 1 Xincheng Road, Dongguan, 523808, China.
Jinbao YinDepartment of Pathology, Guangdong Medical University, 1 Xincheng Road, Dongguan, 523808, China.
Min DengCancer Hospital and Cancer Research Institute, Guangzhou Medical University, Guangzhou, 510095, China. mindeng2016@163.com.
Wei ZhuDepartment of Pathology, Guangdong Medical University, 1 Xincheng Road, Dongguan, 523808, China. zhuw168@126.com.
Chao ZengDepartment of Pathology, Guangdong Medical University, 1 Xincheng Road, Dongguan, 523808, China. zengchaosysu@126.com.
Guangdong Medical College · CNGuangzhou Medical University · CNSun Yat-sen University · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent observations revealed Foxp3 participated in the development of cervical cancer. Furthermore, Foxp3 has a vital function in the lymphatic metastasis of cervical cancer. However, it is unclear whether Foxp3 is correlated with lymphangiogenesis of cervical cancer.

methodsIn this experiment, expression of Foxp3 and VEGF-C was detected in 50 cervical cancer samples by immunohistochemistry. In addition, we evaluated the association between Foxp3 and VEGF-C expression and lymphangiogenesis of cervical cancer evaluated by lymphatic vessel density.

resultsThese data demonstrate Foxp3 is positively correlated with VEGF-C expression. Furthermore, Foxp3 is associated with lymphangiogenesis of cervical cancer.

conclusionsThese results revealed Foxp3 play an important role in lymphangiogenesis of cervical cancer.

trial registrationGunagdong Medical University, PJ2013049.

Indexed as

LymphangiogenesisAntibodies, Monoclonal, Murine-DerivedFemaleForkhead Transcription FactorsHumansImmunohistochemistryLymphatic MetastasisLymphatic VesselsMiddle AgedUterine Cervical NeoplasmsVascular Endothelial Growth Factor CAntibodies, Monoclonal, Murine-DerivedForkhead Transcription FactorsFOXP3 protein, humanmonoclonal antibody D2-40Vascular Endothelial Growth Factor CVEGFC protein, humanCervical cancerFoxp3Lymphangiogenesis

Identifiers

PMID28923073
PMCPMC5604510
OpenAlexW2755421488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.