Evidence map›Paper›PMID 28922523›Full record

ArticleWound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society2017

Mature B cells accelerate wound healing after acute and chronic diabetic skin lesions.

Ruxandra F Sîrbulescu, Chloe K Boehm, Erin Soon, Moses Q Wilks, Iulian Ilieş, Hushan Yuan, Ben Maxner, Nicolas Chronos, Charalambos Kaittanis, Marc D Normandin and 4 more

Open access · greenAbstract read
In one paragraph

Article in Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 120 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Intraparenchymal B cell therapy protects neurological function and modulates local neuroinflammation in experimental hemorrhagic stroke.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Immunomodulatory Delivery Materials for Tissue Repair.Advanced healthcare materials · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Pharmaceuticals (Basel, Switzerland) · 2024
    Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Ruxandra F SîrbulescuVaccine and Immunotherapy Center, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0001-7905-1713
Chloe K BoehmVaccine and Immunotherapy Center, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Erin SoonVaccine and Immunotherapy Center, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Moses Q WilksGordon Center for Medical Imaging, Nuclear Medicine and Molecular Imaging, Radiology Department, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Iulian IlieşHealthcare Systems Engineering Institute, Department of Mechanical and Industrial Engineering, College of Engineering, Northeastern University, Boston, Massachusetts.
Hushan YuanGordon Center for Medical Imaging, Nuclear Medicine and Molecular Imaging, Radiology Department, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Ben MaxnerVaccine and Immunotherapy Center, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Nicolas ChronosVaccine and Immunotherapy Center, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Charalambos KaittanisGordon Center for Medical Imaging, Nuclear Medicine and Molecular Imaging, Radiology Department, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Marc D NormandinGordon Center for Medical Imaging, Nuclear Medicine and Molecular Imaging, Radiology Department, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Georges El FakhriGordon Center for Medical Imaging, Nuclear Medicine and Molecular Imaging, Radiology Department, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Dennis P OrgillDivision of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Ann E SluderVaccine and Immunotherapy Center, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Mark C PoznanskyVaccine and Immunotherapy Center, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Harvard University · USBrigham and Women's Hospital · USNortheastern University · US

Funding

VectorP30CA006516 · NCI · DANA-FARBER CANCER INSTITUTE · PI JENNIFER W MACK · 1985 to 2026
$330.6M
Postgraduate Training Program in Medical Imaging (PTPMI)T32EB013180 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Ciprian Catana, Pedram Heidari · 2011 to 2026
$3.7M
PEG-like Multimodal Nanoprobes for Imaging Enhanced Permeability RetentionR01EB017699 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI NORMANDIN, MARC DAVID · 2014 to 2017
$1.6M
NCI NIH HHS P30 CA006516NIBIB NIH HHS R01 EB017699NIBIB NIH HHS T32 EB013180
6 · The paper itself

Abstract

Chronic wounds affect 12-15% of patients with diabetes and are associated with a drastic decrease in their quality of life. Here, we demonstrate that purified mature naive B220

Indexed as

B-LymphocytesAcute DiseaseAnimalsBiopsyCell- and Tissue-Based TherapyCell SurvivalChronic DiseaseDiabetes Mellitus, ExperimentalFlow CytometryMaleMiceMice, Inbred C57BLMicroscopy, ConfocalSkinSkin DiseasesWound Healing

Identifiers

PMID28922523
PMCPMC5760362
OpenAlexW2754665588

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.