Evidence map›Paper›PMID 28921654›Full record

ArticleAlcoholism, clinical and experimental research2017

Influence of Cocaine-Related Images and Alcohol Administration on Inhibitory Control in Cocaine Users.

Erika Pike, Katherine R Marks, William W Stoops, Craig R Rush

Abstract readControlled Clinical Trial
In one paragraph

Article in Alcoholism, clinical and experimental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Erika PikeDepartment of Behavioral Science, University of Kentucky College of Medicine, Lexington, Kentucky.
Katherine R MarksDepartment of Behavioral Science, University of Kentucky College of Medicine, Lexington, Kentucky.
William W StoopsDepartment of Behavioral Science, University of Kentucky College of Medicine, Lexington, Kentucky.
Craig R RushDepartment of Behavioral Science, University of Kentucky College of Medicine, Lexington, Kentucky.ORCID http://orcid.org/0000-0002-0814-8558
University of Kentucky · US

Funding

Research Training in Drug Abuse BehaviorT32DA035200 · NIDA · UNIVERSITY OF KENTUCKY · PI CRAIG R RUSH, William Walton Stoops · 2013 to 2026
$4.4M
Topiramate-Phentermine Combinations for Cocaine DependenceR01DA036827 · NIDA · UNIVERSITY OF KENTUCKY · PI RUSH, CRAIG R · 2014 to 2017
$1.9M
A Novel Anti Obesity Drug Combination as a Pharmacotherapy for Cocaine DependenceR01DA032254 · NIDA · UNIVERSITY OF KENTUCKY · PI RUSH, CRAIG R · 2012 to 2015
$1.9M
Agonist Replacement Therapy for Methamphetamine Dependence: Human Lab StudiesR01DA025032 · NIDA · UNIVERSITY OF KENTUCKY · PI RUSH, CRAIG R · 2009 to 2013
$1.8M
GABAA Modulation as a Target for Developing Medications for Methamphetamine AbuseR01DA025591 · NIDA · UNIVERSITY OF KENTUCKY · PI RUSH, CRAIG R · 2008 to 2012
$1.4M
Monoamine Uptake Inhibition for Cocaine Dependence: A Novel Drug CombinationR56DA041201 · NIDA · UNIVERSITY OF KENTUCKY · PI RUSH, CRAIG R · 2016 to 2016
$532k
Kentucky Center for Clinical and Translational ScienceTL1TR000115 · NCATS · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2012 to 2015
$518k
NCATS NIH HHS TL1 TR000115NIDA NIH HHS R01 DA025032NIDA NIH HHS R01 DA025591NIDA NIH HHS R01 DA032254NIDA NIH HHS R01 DA036827NIDA NIH HHS R56 DA041201NIDA NIH HHS T32 DA035200
6 · The paper itself

Abstract

backgroundAlcohol use and impulsivity, including decreased inhibitory control, predict poor treatment outcomes for individuals with cocaine use disorders. This study sought to determine the effects of alcohol administration on inhibitory control following cocaine-related and neutral cues on the Attentional Bias-Behavioral Activation (ABBA) task in cocaine users. We hypothesized that the proportion of inhibitory failures would increase following cocaine, compared to neutral, cues. We further hypothesized that there would be an interaction between alcohol administration and task version, such that alcohol would impair inhibitory control following cocaine, but not neutral cues.

methodsFifty current cocaine users completed this mixed-model, double-blind, placebo-controlled, crossover study over 2 experimental sessions. The ABBA task was completed following alcohol administration (0.0 and 0.65 g/kg). Subject-rated drug effect and physiological measures were collected prior to and after alcohol administration.

resultsProportion of inhibitory failures was increased following cocaine-related cues compared to neutral cues independent of alcohol dose. Alcohol administration also produced prototypical subject-rated drug effects.

conclusionsA better understanding of the relationship between alcohol consumption and inhibitory control in cocaine users could direct the development of interventions to decrease the risk of relapse in individuals who drink and display impaired inhibitory control.

Indexed as

Inhibition, PsychologicalAdultCocaineCross-Over StudiesCuesDouble-Blind MethodDrug SynergismDrug UsersEthanolFemaleHumansMalePhotic StimulationYoung AdultCocaineEthanolAlcoholCocaineCocaine CuesInhibitory ControlResponse Inhibition

Identifiers

PMID28921654
PMCPMC5711585
OpenAlexW2755423244

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.