Evidence map›Paper›PMID 28921520›Full record

ArticleInternational journal of cancer2018

Anti-Müllerian hormone and risk of ovarian cancer in nine cohorts.

Seungyoun Jung, Naomi Allen, Alan A Arslan, Laura Baglietto, Aurelio Barricarte, Louise A Brinton, Brian L Egleston, Roni T Falk, Renée T Fortner, Kathy J Helzlsouer and 21 more

Open access · bronzeAbstract read
In one paragraph

Article in International journal of cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Association of Anti-Mullerian Hormone, Follicle-Stimulating Hormone, and Inhibin B with Risk of Ovarian Cancer in the Janus Serum Bank.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 20 institutions in 14 countries.

Seungyoun JungDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0002-9887-2389
Naomi AllenClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Alan A ArslanDepartment of Obstetrics and Gynecology, New York University School of Medicine, New York, NY.
Laura BagliettoCancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Australia.
Aurelio BarricarteNavarra Public Health Institute, Pamplona, Spain.
Louise A BrintonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.ORCID 0000-0003-3853-8562
Brian L EglestonFox Chase Cancer Center, Philadelphia, PA.
Roni T FalkDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.
Renée T FortnerDivision of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany.ORCID 0000-0002-1426-8505
Kathy J HelzlsouerDivision of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD.
Yutang GaoDepartment of Epidemiology, Shanghai Cancer Institute, Shanghai, China.
Annika IdahlDepartment of Clinical Sciences, Obstetrics and Gynecology, Umeå University, Umeå, Sweden.
Rudolph KaaksDivision of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany.
Vittorio KroghFondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.ORCID 0000-0003-0122-8624
Melissa A MerrittDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Eva LundinDepartment of Medical Biosciences, Pathology, and Public Health and Clinical Medicine: Nutritional Research, Umeå University, Umeå, Sweden.
N Charlotte Onland-MoretDepartment of Epidemiology, UMC Utrecht Julius Center, Uretcht, The Netherlands.
Sabina RinaldiInternational Agency for Research on Cancer, Lyon, France.
Helena SchockDivision of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany.
Xiao-Ou ShuDepartment of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN.
Patrick M SlussDepartment of Pathology, Harvard Medical School, Boston, MA.
Paul N StaatsDepartment of Pathology, University of Maryland School of Medicine, Baltimore, MD.
Carlotta SacerdoteUnit of Cancer Epidemiology, Città della Salute e della Scienza University-Hospital and Center for Cancer Prevention (CPO), Turin, Italy.ORCID 0000-0002-8008-5096
Ruth C TravisCancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom.
Anne TjønnelandDanish Cancer Society Research Center, Copenhagen, Denmark.
Antonia TrichopoulouHellenic Health Foundation, Athens, Greece.
Shelley S TworogerDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Kala VisvanathanDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Elisabete WeiderpassDepartment of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.
Anne Zeleniuch-JacquotteDepartments of Population Health and Environmental Medicine and Perlmutter Cancer Center, New York University School of Medicine, New York, NY.
Joanne F DorganDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD.
German Cancer Research Center · DEUniversity of Maryland, Baltimore · USJohns Hopkins University · USNational Cancer Institute · USNew York University · USUmeå University · SEUniversity of Oxford · GBBrigham and Women's Hospital · USCentre international de recherche sur le cancer · FRDanish Cancer Society · DKFondazione IRCCS Istituto Nazionale dei Tumori · ITFox Chase Cancer Center · USHarvard University · USImperial College London · GBInstituto de Salud Pública de Navarra · ESKarolinska Institutet · SENational and Kapodistrian University of Athens · GRPiedmont Reference Center for Epidemiology and Cancer Prevention · ITShanghai Cancer Institute · CNThe University of Melbourne · AU

Funding

Hormone-Related CancersZIACP010126 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI GIERACH, GRETCHEN · 2009 to 2025
$103.5M
Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1M
Statistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI TWOROGER, SHELLEY S · 2000 to 2019
$77.8M
RESEARCH IN ENVIRONMENTAL HEALTH SCIENCES (CENTER GRANT)P30ES000260 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COSTA, MAX · 1985 to 2020
$26.1M
Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
BIOCHEMICAL MARKERS IN THE NURSES'HEALTH STUDY COHORTR01CA049449 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI HANKINSON, SUSAN E · 1989 to 2008
$11.3M
Shanghai Womens Health StudyUM1CA182910 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZHENG, WEI · 2014 to 2018
$5.9M
Cancer Risk Reduction and Diet: A Cohort Study of WomenR37CA070867 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZHENG, WEI · 2009 to 2013
$4.7M
The NYU Women's Health StudyUM1CA182934 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ZELENIUCH-JAQUOTTE, ANNE · 2015 to 2019
$3.7M
Biomarkers and Breast Cancer Risk Prediction in Younger WomenR01CA178949 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LIU, MENGLING, ZELENIUCH-JAQUOTTE, ANNE · 2013 to 2015
$1.9M
Prospective Study of Serum MIS and Gynecologic Cancer RiskR01CA163018 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI DORGAN, JOANNE F · 2012 to 2014
$1.5M
Cancer Research UK 14136Cancer Research UK 16491Medical Research Council G0401527Medical Research Council G1000143Medical Research Council MR/M012190/1Medical Research Council MR/N003284/1NCI NIH HHS P01 CA087969NCI NIH HHS P30 CA016087NCI NIH HHS R01 CA049449NCI NIH HHS R01 CA163018NCI NIH HHS R01 CA178949NCI NIH HHS R37 CA070867NCI NIH HHS UM1 CA182910NCI NIH HHS UM1 CA182934NCI NIH HHS UM1 CA186107NIEHS NIH HHS P30 ES000260World Health Organization 001
6 · The paper itself

Abstract

Animal and experimental data suggest that anti-Müllerian hormone (AMH) serves as a marker of ovarian reserve and inhibits the growth of ovarian tumors. However, few epidemiologic studies have examined the association between AMH and ovarian cancer risk. We conducted a nested case-control study of 302 ovarian cancer cases and 336 matched controls from nine cohorts. Prediagnostic blood samples of premenopausal women were assayed for AMH using a picoAMH enzyme-linked immunosorbent assay. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using multivariable-adjusted conditional logistic regression. AMH concentration was not associated with overall ovarian cancer risk. The multivariable-adjusted OR (95% CI), comparing the highest to the lowest quartile of AMH, was 0.99 (0.59-1.67) (P

Indexed as

Adenocarcinoma, Clear CellAdenocarcinoma, MucinousAdultAnti-Mullerian HormoneBiomarkersCase-Control StudiesCohort StudiesCystadenocarcinoma, SerousEndometrial NeoplasmsFemaleFollow-Up StudiesHumansMiddle AgedNeoplasm GradingNeoplasm StagingOvarian NeoplasmsAnti-Mullerian HormoneBiomarkersanti-Müllerian hormoneepidemiologyovarian cancerovarian function

Identifiers

PMID28921520
PMCPMC5749630
OpenAlexW2755966584

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.