Evidence map›Paper›PMID 28921388›Full record

ArticleInflammopharmacology2017

Immunomodulatory potential of nanocurcumin-based formulation.

Mahendra Kumar Trivedi, Sambhu Charan Mondal, Mayank Gangwar, Snehasis Jana

Abstract read
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In one paragraph

Article in Inflammopharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mahendra Kumar TrivediTrivedi Global, Inc., Henderson, USA.
Sambhu Charan MondalTrivedi Science Research Laboratory Pvt. Ltd., Bhopal, Madhya Pradesh, India.
Mayank GangwarTrivedi Science Research Laboratory Pvt. Ltd., Bhopal, Madhya Pradesh, India.
Snehasis JanaTrivedi Science Research Laboratory Pvt. Ltd., Bhopal, Madhya Pradesh, India. jana@trivedisrl.com.
Translational Research Platform for Veterinary Biologicals (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamins, minerals, and nanocurcumin play a substantial role in various nutraceutical/pharmaceutical formulations that are widely used in therapeutics, cosmetics, and dietary supplements. The current study aimed to investigate the comparative in vitro immunomodulatory effect of a novel nanocurcumin-based formulation with curcumin in LPS-induced cytokine expression, NK cells' activity, and phagocytosis. The proinflammatory cytokines (TNF-α, IL-1β, and MIP-1α) and NK cells' activity were measured in cell supernatants using ELISA assay; however, phagocytosis activity was performed using colorimetric analysis. The chemical characterization of novel nanocurcumin-based formulation using LC-MS (R

Indexed as

AnimalsCell LineCell Line, TumorChemistry, PharmaceuticalCurcuminCytokinesImmunologic FactorsInterleukin-1betaKiller Cells, NaturalLymphocyte ActivationMaleMiceMice, Inbred C57BLNanoparticlesPhagocytosisRAW 264.7 CellsCurcuminCytokinesImmunologic FactorsInterleukin-1betaTumor Necrosis Factor-alphaImmunomodulationLiquid chromatography-mass spectrometryNanocurcuminNatural killer cellsPhagocytosisPro-inflammatory cytokines

Identifiers

PMID28921388
OpenAlexW2754653348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.