Evidence map›Paper›PMID 28920571›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2017

Recurrent seasonal outbreak of an emerging serotype of Shiga toxin-producing Escherichia coli (STEC O55:H7 Stx2a) in the south west of England, July 2014 to September 2015.

Noëleen McFarland, Nick Bundle, Claire Jenkins, Gauri Godbole, Amy Mikhail, Tim Dallman, Catherine O'Connor, Noel McCarthy, Emer O'Connell, Juli Treacy and 16 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Comparative Genomics ofMicroorganisms · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Shiga toxin-producingJournal of medical microbiology · 2020
    Article
  10. Recent Updates on Outbreaks of Shiga Toxin-ProducingFrontiers in cellular and infection microbiology · 2020
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Noëleen McFarlandHealth Protection Team (Fareham), Public Health England South East Centre, Fareham, United Kingdom.
Nick BundleThese authors contributed equally to this article and share first authorship.
Claire JenkinsGastrointestinal Bacteria Reference Unit, National Infection Service, Public Health England, London, United Kingdom.
Gauri GodboleReference Microbiology Services, National infection Service, Public Health England, London, United Kingdom.
Amy MikhailGastrointestinal Infection Department, National Infection Service, Public Health England, London, United Kingdom.
Tim DallmanGastrointestinal Bacteria Reference Unit, National Infection Service, Public Health England, London, United Kingdom.
Catherine O'ConnorEmerging Infections and Zoonoses, National infection Service, Public Health England, London, United Kingdom.
Noel McCarthyField Epidemiology Services, National Infection Service, Public Health England, London, United Kingdom.
Emer O'ConnellField Epidemiology Services, National Infection Service, Public Health England, London, United Kingdom.
Juli TreacyHealth Protection Team (Fareham), Public Health England South East Centre, Fareham, United Kingdom.
Girija DabkeHealth Protection Team (Fareham), Public Health England South East Centre, Fareham, United Kingdom.
James MapstonePublic Health England South of England Region, Bristol, United Kingdom.
Yvette LandyBournemouth Borough Council, Bournemouth, United Kingdom.
Janet MooreWeymouth & Portland Borough Council and West Dorset District Council, Weymouth, United Kingdom.
Rachel PartridgePublic Health Dorset, Dorchester, United Kingdom.
Frieda JorgensenFood Water and Environmental Microbiology Laboratory, National Infection Service, Public Health England, Salisbury, United Kingdom.
Caroline WillisFood Water and Environmental Microbiology Laboratory, National Infection Service, Public Health England, Salisbury, United Kingdom.
Piers MookField Epidemiology Services, National Infection Service, Public Health England, London, United Kingdom.
Chas RawlingsField Epidemiology Services, National Infection Service, Public Health England, London, United Kingdom.
Richard AcornleyEnvironment Agency, Wessex, Blandford, United Kingdom.
Charlotte FeatherstoneAnimal and Plant Health Agency, Thirsk, United Kingdom.
Sharleen GayleFood Standards Agency, London, United Kingdom.
Joanne EdgeFood Standards Agency, London, United Kingdom.
Eleanor McNamaraPublic Health Laboratory, Health Service Executive, Dublin, Republic of Ireland.
Jeremy HawkerField Epidemiology Services, National Infection Service, Public Health England, London, United Kingdom.
Sooria BalasegaramField Epidemiology Services, National Infection Service, Public Health England, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The first documented British outbreak of Shiga toxin-producing Escherichia coli (STEC) O55:H7 began in the county of Dorset, England, in July 2014. Since then, there have been a total of 31 cases of which 13 presented with haemolytic uraemic syndrome (HUS). The outbreak strain had Shiga toxin (Stx) subtype 2a associated with an elevated risk of HUS. This strain had not previously been isolated from humans or animals in England. The only epidemiological link was living in or having close links to two areas in Dorset. Extensive investigations included testing of animals and household pets. Control measures included extended screening, iterative interviewing and exclusion of cases and high risk contacts. Whole genome sequencing (WGS) confirmed that all the cases were infected with similar strains. A specific source could not be identified. The combination of epidemiological investigation and WGS indicated, however, that this outbreak was possibly caused by recurrent introductions from a local endemic zoonotic source, that a highly similar endemic reservoir appears to exist in the Republic of Ireland but has not been identified elsewhere, and that a subset of cases was associated with human-to-human transmission in a nursery.

Indexed as

Disease OutbreaksCommunicable Diseases, EmergingDNA, BacterialEnglandEscherichia coli InfectionsEscherichia coli ProteinsHemolytic-Uremic SyndromeHumansMalePolymerase Chain ReactionRecurrenceSequence Analysis, DNASerogroupShiga-Toxigenic Escherichia coliShiga Toxin 2DNA, BacterialEscherichia coli ProteinsShiga Toxin 2Boot sock study, STEC 055cattle testingNew strainoutbreakpetsSTEC

Identifiers

PMID28920571
PMCPMC5685211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.