Evidence map›Paper›PMID 28920012›Full record

ArticleCurrent geriatrics reports2017

Comparative Effectiveness for Glycemic Control in Older Adults with Diabetes.

Michael Quartuccio, Brian Buta, Rita R Kalyani

Abstract read
In one paragraph

Article in Current geriatrics reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Cardiovascular, Metabolic, and Safety Outcomes with Semaglutide by Baseline Age: Post Hoc Analysis of SUSTAIN 6 and PIONEER 6.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
    Article
  2. Article
  3. Article
  4. Hormones and Aging: An Endocrine Society Scientific Statement.The Journal of clinical endocrinology and metabolism · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael QuartuccioDivision of Endocrinology, Diabetes & Metabolism, Department of Medicine, The Johns Hopkins University, Baltimore, Maryland.
Brian ButaDepartment of Medicine, The Johns Hopkins University, Baltimore, Maryland.
Rita R KalyaniDivision of Endocrinology, Diabetes & Metabolism, Department of Medicine, The Johns Hopkins University, Baltimore, Maryland.

Funding

Clinical Research&Epidemiology in Diabetes&EndocrinologyT32DK062707 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI TODD T BROWN, Wendy Lynet Bennett · 2002 to 2026
$7.3M
Glucose Insulin and Muscle LossK23DK093583 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI KALYANI, RITA R · 2012 to 2015
$635k
Lean Body Mass and the Development of DiabetesR03DK109163 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI KALYANI, RITA R · 2016 to 2017
$174k
NIDDK NIH HHS K23 DK093583NIDDK NIH HHS R03 DK109163NIDDK NIH HHS T32 DK062707
6 · The paper itself

Abstract

purpose of reviewTo review and summarize the current data for comparative effectiveness of glycemic control in older adults. RECENT

findingsIn the last several years, professional societies have released guidelines for glycemic control in older adults, generally recommending individualized HbA1c goals. However, recent observational studies demonstrate that many older adults remain aggressively managed and are at increased risk of hypoglycemia. Large randomized trials of older adults with diabetes have failed to show cardiovascular benefit from intensive glycemic control and show only minimal microvascular benefit. Additionally, a few studies suggest that suboptimal glycemic control can increase the risk for geriatric syndromes. Emerging research suggests similar safety and efficacy of glucose-lowering therapies in older versus younger adults. SUMMARY: Overall, there is a paucity of data supporting the benefit of intensive glycemic control in older adults. More research is needed in this vulnerable population.

Indexed as

age effectscomparative effectivenessdiabeteselderlygeriatricglycemic contrololder adults

Identifiers

PMID28920012
PMCPMC5585298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.