Evidence map›Paper›PMID 28919891›Full record

ArticleFrontiers in microbiology2017

Moderate-Intensity Exercise Affects Gut Microbiome Composition and Influences Cardiac Function in Myocardial Infarction Mice.

Zuheng Liu, Hai-Yue Liu, Haobin Zhou, Qiong Zhan, Wenyan Lai, Qingchun Zeng, Hao Ren, Dingli Xu

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed.

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  7. Exercise benefits in metabolism on cardiovascular disease.Frontiers in cardiovascular medicine · 2026
    Review
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zuheng LiuState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical UniversityGuangzhou, China.
Hai-Yue LiuKey Laboratory for Organ Failure Research, Ministry of Education of the People's Republic of ChinaGuangzhou, China.
Haobin ZhouState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical UniversityGuangzhou, China.
Qiong ZhanState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical UniversityGuangzhou, China.
Wenyan LaiState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical UniversityGuangzhou, China.
Qingchun ZengState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical UniversityGuangzhou, China.
Hao RenKey Laboratory for Organ Failure Research, Ministry of Education of the People's Republic of ChinaGuangzhou, China.
Dingli XuState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical UniversityGuangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical exercise is commonly regarded as protective against cardiovascular disease (CVD). Recent studies have reported that exercise alters the gut microbiota and that modification of the gut microbiota can influence cardiac function. Here, we focused on the relationships among exercise, the gut microbiota and cardiac function after myocardial infarction (MI). Four-week-old C57BL/6J mice were exercised on a treadmill for 4 weeks before undergoing left coronary artery ligation. Cardiac function was assessed using echocardiography. Gut microbiomes were evaluated post-exercise and post-MI using 16S rRNA gene sequencing on an Illumina HiSeq platform. Exercise training inhibited declines in cardiac output and stroke volume in post-MI mice. In addition, physical exercise and MI led to alterations in gut microbial composition. Exercise training increased the relative abundance of

Indexed as

16S rRNAcardiac functionexercisegut microbiomemyocardial infarction

Identifiers

PMID28919891
PMCPMC5585143

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.